Clinical Studies

At SkinCeuticals, we hold our clinical studies to the highest medical and pharmaceutical standards, and dermatologists oversee our testing. As a result, the findings of our clinical studies translate exactly to how our products perform when used in the real world, on real skin.

Our first clinical study on vitamin C paved the way for antioxidant formulation, and set SkinCeuticals on the path to becoming one of the skincare industry’s most respected product innovators. As one of the first companies to provide scientific evidence that supports its product benefits by publishing clinical studies in respected medical journals, SkinCeuticals continues to raise the bar for skin science. Since the first vitamin C study, SkinCeuticals has been behind some of the most pivotal skincare discoveries in recent history.

rESVERATROL: A unique antioxidant offering a
multi-mechanistic approach for treating aging skin

Patricia Farris MD, Jean Krutmann MD, Yuan-Hong Li MD PhD, David McDaniel MD, and Yevgeniy Krol. J Drugs Dermatol. 2013;12(12):1389-1394

Resveratrol is a botanical antioxidant with diverse biologic effects. This paper reviews the unique antioxidant activity of resveratrol including its anti-aging benefits.

Topical L-Ascorbic Acid Percutanous Absorption Studies

Pinnell, S.R., et al.,Topical L-Ascorbic Acid: Percutaneous Absorption Studies. Dermatol Surg 27:2, 137-142, 2001

SkinCeuticals was the first to discover the exact formulation specifications a topical antioxidant must meet in order to be effective. These parameters have become the gold standard for antioxidant formulation.

Photodamage and Oxidative Stress and Protection Provided by Topical Antioxidants

Pinnell, S.R, J Am Acad Dermatol. 48(1): 1-19, 2003.

In order to provide full-spectrum protection against environmentally caused skin damage, it is imperative to use a topical antioxidant daily. This added protection from free radicals has been proven to prevent skin damage.

Sunscreens Inadequately Protect Against UVA-Induced Free Radicals

Haywood, R., et al, J Invest Dermatol 2006;121:862-868

Sunscreen is essential for shielding skin from UVA and UVB rays, but this pivotal study found that SPF alone only protects skin from up to 55% of damaging free radicals. A SkinCeuticals topical antioxidant + a broad spectrum sunscreen provides complete skin protection.

A Topical Antioxidant Solution Containing Vitamins C and E Stabilized by Ferulic Acid Provides Protection for Human Skin Against Damage Caused by Ultraviolet Irradiation

Pinnell, S. et al. J Am Acad Dermatol. 59(3):418-25, 2008.

With SkinCeuticals third-generation topical antioxidant, C E Ferulic, it is possible to provide the skin with eight times environmental protection, as well as unprecedented anti-aging results.

Protective Effects of a Topical Antioxidant Containing Vitamin C, Ferulic Acid and Phloretin Against UV-Induced Photodamage

Oresajo C, Stephens T, Hino PD, Law RM, Yatskayer M, Foltis P, Pillai S, Pinnell SR. J Cosmet Dermatol. 2008 Dec;7(4):290-7.

With the addition of phloretin, SkinCeuticals antioxidants have been clinically proven to improve visible signs of aging while protecting skin from free radicals known to cause skin damage.

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