CLINICAL STUDIES

At SkinCeuticals, we hold our clinical studies to the highest standards and dermatologists oversee our testing. Our products are designed, formulated, and tested for effectiveness, as well as evaluate a product’s efficacy on actual patients’ skin. As a result, the findings of our clinical studies translate exactly to how our products perform when used in the real world, on real skin.

Our first clinical study on vitamin C paved the way for antioxidant formulation, and set SkinCeuticals on the path to becoming one of the skincare industry’s most respected product innovators. As one of the first companies to provide scientific evidence that supports its product benefits by publishing clinical studies in respected peer-reviewed journals, SkinCeuticals continues to raise the bar for skin science. Since the first vitamin C study, SkinCeuticals has been behind some of the most pivotal skincare discoveries in recent history.
Clinical Studies

Clinical Study Topics

ANTIOXIDANT

  • Resveratrol: A Unique Antioxidant Offering a Multi-Mechanistic Approach for Treating Aging Skin
  • Topical L-Ascorbic Acid Percutanous Absorption Studies
  • Photodamage and Oxidative Stress and Protection Provided by Topical Antioxidants
  • A Topical Antioxidant Solution Containing Vitamins C and E Stabilized by Ferulic Acid Provides Protection for Human Skin Against Damage Caused by Ultraviolet Irradiation
  • Protective Effects of a Topical Antioxidant Containing Vitamin C

SUN DAMAGE & PROTECTION

  • Sunscreens Inadequately Protect Against UVA-Induced Free Radicals
Antioxidant
Clinical Study

RESVERATROL: A unique antioxidant offering a multi-mechanistic approach for treating aging skin

Patricia Farris MD, Jean Krutmann MD, Yuan-Hong Li MD PhD, David McDaniel MD, and Yevgeniy Krol. J Drugs Dermatol. 2013;12(12):1389-1394

Resveratrol is a botanical antioxidant with diverse biologic effects. This paper reviews the unique antioxidant activity of resveratrol including its anti-aging benefits.

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Antioxidant
Clinical Study

Topical L-Ascorbic Acid Percutanous Absorption Studies

Pinnell, S.R., et al.,Topical L-Ascorbic Acid: Percutaneous Absorption Studies. Dermatol Surg 27:2, 137-142, 2001

SkinCeuticals was the first to discover the exact formulation specifications a topical antioxidant must meet in order to be effective on skin. These parameters have become the gold standard for antioxidant formulation.

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Antioxidant
Clinical Study

Photodamage and Oxidative Stress and Protection Provided by Topical Antioxidants

Pinnell, S.R, J Am Acad Dermatol. 48(1): 1-19, 2003.

Topical antioxidants provide protection against damaging free radicals that may cause visible signs of aging.

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Sun damage & protection
Clinical Study

Sunscreens Inadequately Protect Against UVA-Induced Free Radicals

Haywood, R., et al, J Invest Dermatol 2006;121:862-868

Sunscreen is essential for protecting skin from UVA and UVB rays, but this pivotal study found that SPF alone only protects skin from up to 55% of damaging free radicals—and that the addition of a SkinCeuticals topical antioxidant provides better skin protection.

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Antioxidant
Clinical Study

A Topical Antioxidant Solution Containing Vitamins C and E Stabilized by Ferulic Acid Provides Protection for Human Skin Against Damage Caused by Ultraviolet Irradiation

Pinnell, S. et al. J Am Acad Dermatol. 59(3):418-25, 2008.

With SkinCeuticals third-generation topical antioxidant, C E Ferulic, it is possible to neutralize UV-induced free radicals, as well as provide anti-aging benefits.

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Antioxidant
Clinical Study

Protective Effects of a Topical Antioxidant Containing Vitamin C, Ferulic Acid and Phloretin Against UV-Induced Photodamage

Oresajo C, Stephens T, Hino PD, Law RM, Yatskayer M, Foltis P, Pillai S, Pinnell SR. J Cosmet Dermatol. 2008 Dec;7(4):290-7.

With the addition of phloretin, SkinCeuticals antioxidants have been shown to improve the appearance of premature signs of aging while protecting skin from damaging free radicals.

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