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A.G.E. Interrupter Wrinkle cream

A.G.E. Interrupter is rated 4.6 out of 5 by 64.
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High-concentration anti-wrinkle cream formulated to improve the visible signs of aging caused by advanced glycation end-products (A.G.E.)

skin types

Dry
Normal
Sensitive

skin condition

Aging

$162.00

Availability:

In Stock

Product Details

A.G.E. Interrupter is an advanced wrinkle treatment that fights the visible signs of aging caused by advanced glycation end-products (A.G.E.), a major factor of the natural aging process. This anti-aging cream is formulated with an unprecedented 30% concentration of proxylane™, 4% blueberry extract, and 0.2% phytosphingosine (pronounced fi'to-sfing'go-sen) to improve the appearance of wrinkling and restore the loss of firmness caused by the glycation process.

  • Reduces the appearance of skin creping and thinning
  • Visibly improves the appearance of fine lines, wrinkles, and skin texture
  • Restores water and nutrients to improve the look of skin firmness
  • Comforts dry, aging skin
  • Alcohol-, and dye-free

How To Use

Skinceuticals

Once or twice daily, massage a thin, even layer onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

  • Visible Results

  • visible results

    In a 12-week study, A.G.E. Interrupter showed a significant improvement in the appearance of wrinkles, firmness, and skin texture

    See Protocol

    A 12-week controlled clinical study on 41 subjects, ages 45-61. Subjects applied A.G.E. Interrupter twice daily.

  • Science & Proof

  • Science

    Intrinsic or natural aging, caused by internal factors such as hormonal shifts and changes in skin metabolism, contribute to the appearance of wrinkles, loss of firmness, and crepy skin.

    Glycation, a major factor of intrinsic aging, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.

    A.G.E. Interrupter is a uniquely-textured formulation optimized to help improve the visible signs of aging associated with glycation. This potent anti-wrinkle cream features a high-concentration combination of proxylane, blueberry extract, and phytosphingosine to improve visible signs of aging such as wrinkles, loss of firmness, and a crepy, thinning appearance.

Key Ingredients

  • 4% Blueberry extract
  • 30% Proxylane™
  • 0.2% Phytosphingosine

Naturally derived and both an antioxidant and anti-glycation ingredient helps fortify skin’s matrix and prevent the appearance of wrinkles and laxity.

Learn more about Blueberry extract

See all ingredients

aqua / water / eau, propylene glycol, dimethicone, hydroxypropyl tetrahydropyrantriol, cyclohexasiloxane, isohexadecane, glycerin, synthetic wax, dimethicone/peg-10/15 crosspolymer, aluminum starch octenylsuccinate, ci 77163 / bismuth oxychloride, phenoxyethanol, magnesium sulfate, ethylhexyl hydroxystearate, salicyloyl phytosphingosine, acrylates copolymer, methylparaben, ethylparaben, disodium edta, vaccinium myrtillus extract / vaccinium myrtillus fruit extract, parfum / fragrance, butylphenyl methylpropional, coumarin

Physician Insight

Physician image

A.G.E Interrupter is an impressive corrective cream that significantly improves the appearance of the visible signs of aging such as fine lines and wrinkles that are common as we age. It is an ideal for various skin types, and is a popular product requested by Park Avenue Medical Spa patients.

Dr. Anca Tchelebi-Moscatello - Park Avenue Medical Spa

Learn about Dr. Tchelebi-Moscatello

Complete Your Regimen

Reviews

Rated 5 out of 5 by from Great product for older skin I bought this product several times and I’m going to order another one after I finish this review. It’s a great anti-aging cream to help firm tone and hydrate older skin. It goes on smooth and it is not the least bit greasy. Makeup Goes on perfectly on top of this cream. Are use it along with the aha hyaluronic acid and the CE ferulic serum. All three products or a life changer!
Date published: 2019-06-08
Rated 5 out of 5 by from Fantastic I have been using this product for a couple of years and I love it! I have super sensitive skin, prone to redness. I had a difficult time finding a product to prevent wrinkles that didn’t irritate my skin until the A.G.E. Interrupter cream. It is a pretty think product so I use it as a moisturizer.
Date published: 2019-06-08
Rated 5 out of 5 by from Best moisturizer I have ever used I have been using this product for over 2 years. Keeps my skin soft and hydrated without ever feeling greasy. I feel like minimizes aging. I frequently get comments about how I have “good skin”. I think I have a good moisturizer!
Date published: 2019-06-08
Rated 5 out of 5 by from Touchable! After my Skinceuticals regimen I just can't quit touching my face. It's so moist and touchable. What a difference in my complexion since I started using these products. LOVE them!
Date published: 2019-06-03
Rated 5 out of 5 by from So far so good I just purchased my first tub of this a few weeks ago and already think I see a difference. I love the consistency of this cream, so silky and light!
Date published: 2019-05-03
Rated 5 out of 5 by from Great results I’ve used this for several years and very happy with the results.
Date published: 2019-04-25
Rated 5 out of 5 by from very silky This is my second jar and I can say that my skin is much brighter and smoother with less discoloration. Maybe a little pricey but last a very long time.
Date published: 2019-04-23
Rated 5 out of 5 by from Smooth Skin I have been using this moisturizer for two months, along with the A.G.E. eye cream. The formula is non-greasy and brings along an extremely smooth, almost matte-like appearance to my skin. It can feel a little heavy when first applied, but quickly absorbs into my skin. I use it daily in the morning and have received so many compliments lately on how smooth my face looks.
Date published: 2019-04-22
Rated 5 out of 5 by from Love This! Thick and creamy. This really helps with my dry skin and fine lines and wrinkles. Highly recommend. My only complaint is sometimes they are out of the product and you have to wait, which is frustrating.
Date published: 2019-04-22
Rated 5 out of 5 by from Love Love Love this moisturizer! Dreamy... I have added this product to my evening skin regemin. It is silky smooth and leaves my skin feeling so hydrated and soft. I recommend this product to anyone who wants to visibly improve their skin and promise that you will receive compliments! I can’t live without it.
Date published: 2019-04-21
Rated 5 out of 5 by from Definitely worth the investment! I have been using SkinCeuticals Age Interrupter cream for about two years. I usually apply once daily before bed. I have very sensitive skin and have never had a problem with this cream (as I have with many others I've tried). I am 60 years old and when I tell people my age, they are always shocked and tell me I don't even look 50. I think my daily regimen of SkinCeuticals skin care products, and watching my sun exposure with using SkinCeuticals sunscreen, are to thank.
Date published: 2019-04-20
Rated 5 out of 5 by from My Favorite It is hard for me to pick my favorite Skin Ceuticals product but if I had to pick the one that I could not give up it would be AGE Interrupter. I have been using it for about 8 years and I love what it has done for my skin!
Date published: 2019-04-20
Rated 5 out of 5 by from fabulous! Use this mostly on my neck and decollate - and it's amazing! I'm 56 and have started to get 'device neck', wrinkles and creepiness around my neck from constantly looking at my phone, iPad of laptop. This cream (although pricey!) has taken YEARS off the appearance of my skin in the delicate neck/chest. A must have. Won't live without it!
Date published: 2019-04-20
Rated 5 out of 5 by from Worth it! I am almost 50 and was really struggling with dry patches on my chin- my moisturizer would work in the morning but by lunch my skin was dry, tight, and cracked with deep lines. This is the only moisturizer that keeps my skin looking great all day—dewy, not oily. I’ve seen diminished lines around my mouth and my chin dryness is totally gone. I hesitated to spend the money at first but am now completely sold on this product and will buy it again!
Date published: 2019-04-19
Rated 5 out of 5 by from Beautiful texture, rich without being greasy. This cream has a mattifying, smoothing effect, and is the only cream I've ever used where I've noticed a distinct difference in my skin.
Date published: 2019-04-19
Rated 5 out of 5 by from It works!! It works!! It has a filler effect. It made my skin much firmer. I'm 34 years old.
Date published: 2019-04-11
Rated 5 out of 5 by from Actually Works I'm a 31 year old male with combination skin and I've been using A.G.E, Interrupter right around 5 weeks and just re-purchased. The product works. I've used plenty of moisturizers that did moisturize but would also leave me greasy or products that claimed anti-aging and ended up being nothing but mediocre moisturizers. This product moisturizes, firms, and does all it claims. The softening of fine lines and wrinkles is why I'm leaving this review. My forehead wrinkles are pretty deep from work and life but there's a tiny difference. The big visible difference are my smile lines. There's a visible difference and I'm shocked. It's subtle and they are realistic changes but it's so cool to see the change from this product after 5 weeks. It's pretty pricey but I don't mind paying for quality, though a bit of break every now and then would be nice. They caught a loyal customer for as long as they want me.
Date published: 2019-04-11
Rated 5 out of 5 by from Wont do without this, my daughter gave me this for my birthday , I dont what it cost Ill never be without it!!! The difference in my skin is amazing, very gentle but noticeable.
Date published: 2019-03-28
Rated 5 out of 5 by from Wrinkle Eraser I have bought this multiple times and cannot imagine life without it. I constantly get complements on my skin. A.G.E. Interrupter truly makes a difference.
Date published: 2019-03-27
Rated 4 out of 5 by from I've used this as a night Cream and really liked it. Definitely moisturizing and gave a beautiful finish. For my combo skin it was a bit too heavy for day time, but great for night. Skinceuticals is a brand that I consistently have success with and this was no exception.
Date published: 2019-02-26
Rated 4 out of 5 by from I had never used any SkinCeuticals products before this one. The thing I love the most about this cream is the consistency! It's not heavy at all but leaves your skin feeling super hydrating without being too greasy. It's great for combination skin- Although I haven't seen any tangible results of removing fine lines, I do love this cream. Only reason I didn't give it 5 stars was the price- quite high in my opinion.
Date published: 2019-02-26
Rated 5 out of 5 by from Want to maintain your youthful appearance? This is a must have! This was recommended to me by my dermatologist and haven't turned back since.
Date published: 2019-02-26
Rated 5 out of 5 by from Love this face cream! On the heavier side, so a good night option. Pricey, but worth it. I have been using this for years now. Bought at my local dermatologists office and would buy again. Good anti-aging product!
Date published: 2019-02-26
Rated 4 out of 5 by from So far so good! No crazy reactions or redness. Just started using this product along with the eye cream! I alternate with other products each night. A bit on the expensive side - but maybe worth it!
Date published: 2019-02-26
Rated 4 out of 5 by from This product is great for mature skin. Has a very light fragrance and velvety texture. Product is used as a corrector so underneath your moisturizer.
Date published: 2019-02-26
Rated 5 out of 5 by from I recently noticed fine lines beginning to form on my forehead and was thinking Botox would have to be my next step. Soon after, my sister bought me the A.G.E. Interrupter cream along with the C E Ferulic daytime serum and the Resveratrol B E nighttime serum. I used these 3 products religiously and after a month I could see a HUGE difference! My forehead lines had faded and my skin felt hydrated and renewed. I eventually ran out of the cream and the fine lines did not immediately come back! This told me that the product was actually working on my skin and was not just a short term fix. I don't think I will ever try another moisturizer again.
Date published: 2019-02-26
Rated 3 out of 5 by from Skin feels great, not sure it’s worth the price I’ve only been using the AGE Interrupter for little more than a month. I am in my 50’s and have combination skin. I’ve noticed my skin is softer and I haven’t experienced any breakouts. I haven’t noticed a reduction in subtle lines or wrinkles (I took a before photo). The other negative I’ve experienced is, I wear my hair over my forehead (to help conceal wrinkles) and have been dealing with my hair looking very oily before the end of the day. Before I started using this product I would be able to go 2-3 days between shampoos.
Date published: 2019-01-26
Rated 5 out of 5 by from Best Wrinkle Cream On the Market This is the one product that keeps me coming back to SkinCeuticals. I have added other SkinCeutical products to my regimen, but this is the key. And when I'm in a hurry, this is the one I never skip and I carry a sample in my purse. I see visible results immediately as it smooths the wrinkles on my cheeks, around my mouth, on my forehead and even on my neck. I'm 67 and I've tried other wrinkle creams but nothing is as effective as this one in making my skin look smoother and younger.
Date published: 2018-12-07
Rated 5 out of 5 by from Best of the Best I can’t say enough about A.G.Interrupter. It moisturizes nicely and gives face a healthy, hydrated glow while not causes any blemishes or acne outbreaks. Use it morning and evening. It is rather expensive but worth every cent.
Date published: 2018-11-25
Rated 5 out of 5 by from The BEST anti-aging cream I know that this review is long but I felt like I needed to share! I have been semi-obsessed with anti-aging products for the past few years. I recently noticed fine lines beginning to form on my forehead and was thinking Botox would have to be my next step. Soon after, my sister bought me the A.G.E. Interrupter cream along with the C E Ferulic daytime serum and the Resveratrol B E nighttime serum. I used these 3 products religiously and after a month I could see a HUGE difference! My forehead lines had faded and my skin felt hydrated and renewed. I eventually ran out of the cream and the fine lines did not immediately come back! This told me that the product was actually working on my skin and was not just a short term fix. I don't think I will ever try another moisturizer again.
Date published: 2018-11-08
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