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A.G.E. Interrupter Wrinkle cream

A.G.E. Interrupter is rated 4.6 out of 5 by 101.
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High-concentration anti-wrinkle cream formulated to improve the visible signs of aging caused by advanced glycation end-products (A.G.E.)

skin types

Dry
Normal
Sensitive

skin condition

Aging

$162.00

Availability:

In Stock

Product Details

A.G.E. Interrupter is an advanced wrinkle treatment that fights the visible signs of aging caused by advanced glycation end-products (A.G.E.), a major factor of the natural aging process. This anti-aging cream is formulated with an unprecedented 30% concentration of proxylane™, 4% blueberry extract, and 0.2% phytosphingosine (pronounced fi'to-sfing'go-sen) to improve the appearance of wrinkling and restore the loss of firmness caused by the glycation process.

  • Reduces the appearance of skin creping and thinning
  • Visibly improves the appearance of fine lines, wrinkles, and skin texture
  • Restores water and nutrients to improve the look of skin firmness
  • Comforts dry, aging skin
  • Alcohol-, and dye-free

How To Use

Skinceuticals

Once or twice daily, massage a thin, even layer onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

  • Visible Results

  • visible results

    In a 12-week study, A.G.E. Interrupter showed a significant improvement in the appearance of wrinkles, firmness, and skin texture

    See Protocol

    A 12-week controlled clinical study on 41 subjects, ages 45-61. Subjects applied A.G.E. Interrupter twice daily.

  • Science & Proof

  • Science

    Intrinsic or natural aging, caused by internal factors such as hormonal shifts and changes in skin metabolism, contribute to the appearance of wrinkles, loss of firmness, and crepy skin.

    Glycation, a major factor of intrinsic aging, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.

    A.G.E. Interrupter is a uniquely-textured formulation optimized to help improve the visible signs of aging associated with glycation. This potent anti-wrinkle cream features a high-concentration combination of proxylane, blueberry extract, and phytosphingosine to improve visible signs of aging such as wrinkles, loss of firmness, and a crepy, thinning appearance.

Key Ingredients

  • 4% Blueberry extract
  • 30% Proxylane™
  • 0.2% Phytosphingosine

Naturally derived and both an antioxidant and anti-glycation ingredient helps fortify skin’s matrix and prevent the appearance of wrinkles and laxity.

Learn more about Blueberry extract

See all ingredients

aqua / water / eau, propylene glycol, dimethicone, hydroxypropyl tetrahydropyrantriol, cyclohexasiloxane, isohexadecane, glycerin, synthetic wax, dimethicone/peg-10/15 crosspolymer, aluminum starch octenylsuccinate, ci 77163 / bismuth oxychloride, phenoxyethanol, magnesium sulfate, ethylhexyl hydroxystearate, salicyloyl phytosphingosine, acrylates copolymer, methylparaben, ethylparaben, disodium edta, vaccinium myrtillus extract / vaccinium myrtillus fruit extract, parfum / fragrance, butylphenyl methylpropional, coumarin

Physician Insight

Physician image

A.G.E Interrupter is an impressive corrective cream that significantly improves the appearance of the visible signs of aging such as fine lines and wrinkles that are common as we age. It is an ideal for various skin types, and is a popular product requested by Park Avenue Medical Spa patients.

Dr. Anca Tchelebi-Moscatello - Park Avenue Medical Spa

Learn about Dr. Tchelebi-Moscatello

Complete Your Regimen

Reviews

Rated 4 out of 5 by from This product is great for mature skin. Has a very light fragrance and velvety texture. Product is used as a corrector so underneath your moisturizer.
Date published: 2019-02-26
Rated 5 out of 5 by from I recently noticed fine lines beginning to form on my forehead and was thinking Botox would have to be my next step. Soon after, my sister bought me the A.G.E. Interrupter cream along with the C E Ferulic daytime serum and the Resveratrol B E nighttime serum. I used these 3 products religiously and after a month I could see a HUGE difference! My forehead lines had faded and my skin felt hydrated and renewed. I eventually ran out of the cream and the fine lines did not immediately come back! This told me that the product was actually working on my skin and was not just a short term fix. I don't think I will ever try another moisturizer again.
Date published: 2019-02-26
Rated 3 out of 5 by from Skin feels great, not sure it’s worth the price I’ve only been using the AGE Interrupter for little more than a month. I am in my 50’s and have combination skin. I’ve noticed my skin is softer and I haven’t experienced any breakouts. I haven’t noticed a reduction in subtle lines or wrinkles (I took a before photo). The other negative I’ve experienced is, I wear my hair over my forehead (to help conceal wrinkles) and have been dealing with my hair looking very oily before the end of the day. Before I started using this product I would be able to go 2-3 days between shampoos.
Date published: 2019-01-26
Rated 5 out of 5 by from Most amazing serum I’ve ever used! It gave me the glow I wanted and evened out my skin tone! Just amazing
Date published: 2019-01-08
Rated 5 out of 5 by from Best Wrinkle Cream On the Market This is the one product that keeps me coming back to SkinCeuticals. I have added other SkinCeutical products to my regimen, but this is the key. And when I'm in a hurry, this is the one I never skip and I carry a sample in my purse. I see visible results immediately as it smooths the wrinkles on my cheeks, around my mouth, on my forehead and even on my neck. I'm 67 and I've tried other wrinkle creams but nothing is as effective as this one in making my skin look smoother and younger.
Date published: 2018-12-07
Rated 5 out of 5 by from Best of the Best I can’t say enough about A.G.Interrupter. It moisturizes nicely and gives face a healthy, hydrated glow while not causes any blemishes or acne outbreaks. Use it morning and evening. It is rather expensive but worth every cent.
Date published: 2018-11-25
Rated 5 out of 5 by from The BEST anti-aging cream I know that this review is long but I felt like I needed to share! I have been semi-obsessed with anti-aging products for the past few years. I recently noticed fine lines beginning to form on my forehead and was thinking Botox would have to be my next step. Soon after, my sister bought me the A.G.E. Interrupter cream along with the C E Ferulic daytime serum and the Resveratrol B E nighttime serum. I used these 3 products religiously and after a month I could see a HUGE difference! My forehead lines had faded and my skin felt hydrated and renewed. I eventually ran out of the cream and the fine lines did not immediately come back! This told me that the product was actually working on my skin and was not just a short term fix. I don't think I will ever try another moisturizer again.
Date published: 2018-11-08
Rated 5 out of 5 by from Best product I bought this and other skinceuticals product one month ago am so happy, my skin looks very different ,smooth and bright. i will alway use it .Thanks.
Date published: 2018-10-06
Rated 5 out of 5 by from A.G.E. Interrupter- Great Eye Cream I had always been hesitant to buy eye creams as Always got allergies or some sort of reaction, or wake up swollen. This cream is amazing and my eyes are much improved and to this date - 6 months later - no reactions. love it!
Date published: 2018-08-09
Rated 4 out of 5 by from Love this product I have been using this for a couple of years and just recently started using it on my neck and chest and I have seen an improvement in the firmness of my skin in my neck. The loose skin on my neck is looking much better
Date published: 2018-07-21
Rated 5 out of 5 by from The magic bullet After trying a zillion skin care products, I can say this is it for me. My skin has never looked better and more supple. I've been using it for 9 months along with the corresponding eye cream, and the bitty signs of aging I had are gone (I'm 40). Often people scoff when they learn my age or check my ID, not believing I'm 40. The price may be steep, but this jar has lasted me the 9 months I've been using it daily. I'm just close to running out, so I'll be reordering very soon. A little goes a long way, and it's worth every penny. The little lines I had on my forehead and under my eyes are completely gone, it's like magic. If you layer the Hydrating B5 Gel under it, your skin will feel and look like the finest silk. My search for a skin product that actually works is over!
Date published: 2018-05-29
Rated 5 out of 5 by from Fountain of Youth in a jar!! This product is awesome!!! I went to a day spa a couple of years ago for a facial and Skinceuticals was recommended for me. The A.G.E. Interruptor is phenomenal!!!nI have combination skin and wasn't sure this would be for me as it is for mature skin but it is fabulous. It is rich and creamy without being heavy. My skin loves it and you will too. I use the whole Skinceuticals regimen and constantly get compliments on my skin. I am turning 50 in a couple of days and people can't believe it. My skin looks years younger. It is pricey but so concentrated. You use so little of it that is lasts a long time. BUY IT!!! You will be so glad you did.
Date published: 2018-04-15
Rated 5 out of 5 by from Amazing Simply the best cream that I have ever purchased and used! I absolutely recommend it !
Date published: 2018-04-01
Rated 1 out of 5 by from Conflicted I bought this a few months ago and it was arguably the best cream that I have ever used. I reordered the product a little over a month ago and was surprised at the results when I started using it again. The thickness of the product is one of the reasons why I was so pleased with it in the first place; however, this time the cream does not rub in well and leaves a film-like residue on my skin, which is especially noticeable if I try to apply makeup over it. I previously wrote an inquiry regarding this product, but never received a response from the company. In fact, I have never received any response from them on the two separate occasions that I have written to them. Maybe since I am writing a review, they will finally care to get back to me.
Date published: 2017-09-18
Rated 5 out of 5 by from My search is over! I have tried every cream there is looking for one that would make a difference in my skin and also not cause sensitivities. This is hands down the best face cream out there. I have sensitive combination skin. I have occasional hormonal breakouts but still am concerned about fine lines and wrinkles. I have used for three days and I am amazed already at the results. my skin is glowing. please skinceuticals never ever discontinue this product. I should also mention I use and love the serums as well.
Date published: 2016-03-23
Rated 5 out of 5 by from AWESOME PRODUCT!!! LOVE THIS!! I use this cream as my 'third step' after CE Ferulic and Hydrating B5 Gel...and finish off with Physical Fusion SPF 50 (4th Step)...Makeup application is a breeze ( I use an airbrush system with a primer) I usually get 12-15 hours of perfection with no makeup reapplication needed..My skin always looks amazing!! I found that all of the products work best when used in conjunction with one another..For reference, I visit my Esthetician every 3 weeks for derma-plane, light peel etc..I do 2 heavy peels yearly combined with laser as needed..
Date published: 2016-01-20
Rated 5 out of 5 by from The Best Moisturizer This is a product that actually works instantly for me! I use it now with the Reversatrol BE. The older I get the more help that I need.
Date published: 2014-05-11
Rated 5 out of 5 by from Superb Product I love love this product it does exactly what is says it will. I am amazed by the results. I have been using it for 5 weeks now along with CE Ferluic and when I look in the mirror I am just amazed! At 60 that is not an easy thing to claim. I was raised at the beach so I have had lots of sun damage but these products have reduced the wrinkles and uneven texture. My skin feels like silk.
Date published: 2014-01-03
Rated 5 out of 5 by from Best Product I Have Ever Used This has got to be the best product I have ever used. I've spent hundreds of dollars on other products that just didn't show any results even after several months of use. A.G.E. Interrupter Works PERIOD. It took about 6 weeks of use for me to notice a difference and what a difference it has made. The lines on my forehead and the dreaded '11' frown lines have been so diminished. The best part is that A.G.E. Interrupter doesn't cause me to breakout like most creams do.nnnnThe texture of the cream is so luxurious and my skin feels nourished but not overly sticky. Yes the price is high but it truly is worth every penny. I'll be buying this again and again.
Date published: 2013-12-04
Rated 5 out of 5 by from It does work! I got this eye cream for puffiness and crow feets. Both are gone. You do have to be patient though. I read the instructions inside the box. It tells how long the process will take to get certain result. I did not see any effect immediately or later but continued to use it as long as it was mentioned in the instructions. And it worked exactly the time period they mentioned. I am happy with the result and will continue to use this.
Date published: 2013-10-28
Rated 5 out of 5 by from Love it! I received a sample after my facial at a local spa and I love it! I am going to purcahse immediately. I love the richness and how smooth my skin feels.
Date published: 2012-02-09
Rated 5 out of 5 by from My search for the perfect skin cream is over! Is it possible to be addicted to a skin care system? It must be because I love my A.G.E Interrupter cream (and all the other products I use with it). I ran out for a few weeks and went back to my old skin cream (a pricey, popular line) and there was no comparison! This cream is so rich and feels so wonderful on my skin...and the results are fantastic! Well worth every penny - finally!
Date published: 2012-01-29
Rated 5 out of 5 by from This product is so effective! I love A.G.E. Interrupter. I have been using this product for over a year now. I have basal cell carcinoma on my forehead from spending years in the sun in the Caribbean and in Hawaii and this is the ONLY product that reduces the redness and scaling. I have sensitive skin and this product makes my skin look brighter and it combats dullness.
Date published: 2011-12-19
Rated 5 out of 5 by from The BEST! This is my favorite product. i like the smell, the texture and the results! It is a bit pricey, but worth it.
Date published: 2011-11-07
Rated 5 out of 5 by from Excellent! I've tried everything and nothing showed any difference in my skin. When I started using Skin Ceuticals, for the first time I noticed a dramatic difference. I even tried L_ Me_ and there was no change. I am a lifer with Skin Ceuticals. My skin is smooth and the skin tone is even and it stays that way unless I use something else. I use C.E. Ferulic with A.G.E. Interrupter at night and the moisterizing serum with the skin tightening lotion during the day. I will never change.
Date published: 2011-08-13
Rated 5 out of 5 by from this product is wonderful My skin was relaly changed after pregnancy. Dry, with open pores, and wrinkly. After one year with Age Interrupter, my skin return back to five years before. Is smooth and balanced.
Date published: 2011-08-09
Rated 5 out of 5 by from This product makes my face feel wonderful! I started to use this product last summer after a long weekend at the beach. It refreshed by face and provided great moisture benefits. I use it in the evening and right after being in the sun. My skin feels more youthful when I use it regularly. I have used it on my children's face if they get a sunburn, and the burn just goes away.
Date published: 2011-07-22
Rated 5 out of 5 by from Outstanding for dry skin. I have tried many different types of moisturizers over the years and this is the first one that keeps my skin hydrated all day long. Most of the lines on my face disappear.
Date published: 2011-07-22
Rated 5 out of 5 by from I think all A.G.E. products are great! Not only would I recommend A.G.E. Interrupter to friends, I have given the product to all of my close relatives for use and recommended it to all of my close friends for their use. I use the products, particular this one, every morning and evening. It gives me a smooth feeling to my face that I have never felt before with any other cream -- not greasy!
Date published: 2011-07-21
Rated 5 out of 5 by from Just wonderful. I go out during the day with confidence I will look the best I can for my age. I have never expected miracles but it is certainly a change from the rough, skin I have been dealing with.
Date published: 2011-06-29
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