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Discoloration Defense Skin discoloration serum

Discoloration Defense is rated 3.5 out of 5 by 117.
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Daily dark spot corrector targets visible skin discoloration for brighter, more even-looking skin

skin types

Dry
Normal
Oily
Combination

skin condition

Discoloration

$98.00

Availability:

In Stock

Product Details

Discoloration Defense is a layerable, daily-use dark spot corrector clinically proven to reduce the appearance of key types of skin discoloration, including hard-to-treat forms such as stubborn brown patches and post-acne marks. Formulated with 3% tranexamic acid, 1% kojic acid, 5% niacinamide, and 5% HEPES, this latest-generation formula improves the appearance of skin discoloration, brightens skin, and evens skin tone in as early as 2 weeks.

  • Features a synergistic blend of anti-discoloration ingredients to reduce the appearance of skin discoloration, improve brightness, and minimize the reoccurrence of discoloration (with continued use)
  • 60% average improvement in the appearance of stubborn brown patches
  • Paraben-, fragrance-, silicone-, gluten-, and hydroquinone-free
  • Ideal at-home complement to professional skin discoloration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations

How To Use

  • Twice daily, apply 3-5 drops of this skin discoloration serum to the face.
  • If using in the morning, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad spectrum SPF 50+ sunscreen.
  • Limit sun exposure while using this product.
  • Do not use on irritated or broken skin. If irritation occurs, discontinue use.
  • Visible Results

  • before
    after

    In a 12-week clinical study, Discoloration Defense significantly improved the appearance of key skin discoloration markers:

    • 60% average improvement in the appearance of stubborn brown patches
    • 59% average improvement in the appearance of skin discoloration
    • 81% average improvement in the appearance of post-acne marks
    • 59% average improvement in the appearance of even skin tone

    See Protocol

    Protocol: Average results shown. A 12-week, single-center, clinical study was conducted on 50 females, ages 25 to 60, Fitzpatrick I-IV, with mild to moderate facial skin discoloration, including stubborn dark spots, post-acne marks, and uneven skin tone. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.

  • Science & Proof


  • Science

    Everyday elements—including UV exposure, prescription drugs, and some professional treatments—can trigger production of melanin in the skin’s lowest epidermal layers. This excess melanin rises to the surface of the skin, causing visible skin discoloration. Discoloration can manifest in a range of ways, including post-acne marks and stubborn brown patches on the cheekbones, forehead, and upper lip.

    Discoloration Defense is the latest-generation dark spot corrector, using a combination of potent and proven anti-discoloration ingredients—including new tranexamic acid—to address key types of skin discoloration.

Key Ingredients

  • 3% Tranexamic Acid
  • 1% Kojic Acid
  • 5% Niacinamide
  • 5% HEPES

This synthetically-derived ingredient minimizes the reoccurrence of skin discoloration and stubborn brown patches with continued use.

Learn more about Tranexamic Acid

See all ingredients

Aqua / Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Tranexamic Acid, Propylene Glycol, Hydroxyethyl Urea, Kojic Acid, Caprylyl Glycol, Allantoin, Chlorphenesin, Xanthan Gum, Disodium Edta

Physician Insight

Physician image

I recommend Discoloration Defense between chemical peels- this formula targets stubborn types of discoloration but is gentle on my patients’ skin, making it ideal for an at-home regimen between treatments.

Dr. Sarah Sawyer

Learn about Dr. Sarah Sawyer

Complete Your Regimen

Reviews

Rated 4 out of 5 by from Great! This product truly improves the appearance of brown spots and hyperpigmentation from old acne.
Date published: 2020-09-27
Rated 5 out of 5 by from Great product, but I think it oxidized? I absolutely love this product. It has been such a game changer for my hyper-pigmentation. However, the serum has turned to a dark orange/brown. Can I still use it?
Date published: 2020-09-15
Rated 1 out of 5 by from Don’t waste your money I bought this to lighten my ugly moles and I’ve been using for a week and there is no change at all. I’ve been trying to get rid of my moles from the sun forever. I’m hopeless now.
Date published: 2020-09-08
Rated 2 out of 5 by from No improvement I've tried many skinceuticals products and some work for my skin and others don't. This on. unfortunately has not at all after using the full bottle. I will go back to Phyto for discoloration which has worked better for me.
Date published: 2020-09-05
Rated 5 out of 5 by from Effective. Received a sample with a order and found it very effective. Absorbs quickly, has no smell (yay!), and I saw results faster than expected. Ordered more before sample was gone. Now a staple in my skin care. Impressed.
Date published: 2020-08-28
Rated 3 out of 5 by from Sample I wish I could give review on the sample product I received. But when I opened the sample packet. It spilled out all over my hand. I can not give you an honest opinion on the product I received except the packaging needs to be improved. But in the past I have used several of Skinceuticals products. I have always been pleased with the results of other products.
Date published: 2020-08-21
Rated 1 out of 5 by from Discoloration Defense I received a sample packet of this when I cut and tried to squeeze out a small amount all of the serum squirted out. Company has to figure out how to better package a sample. I have been using the A.G.E Interrupter for the face for six weeks with no results so I am not purchasing this. These products are not cheap I expect a usable sample and results will not purchase any products in the future.
Date published: 2020-08-17
Rated 5 out of 5 by from Amazing product This was recommended by our dermatologist for treating pigmentation and after 1 month, we can see the pigmentation has faded quite a bit already.
Date published: 2020-08-16
Rated 1 out of 5 by from Review There wasn't enough on that sample sheet to be able to tell a difference.
Date published: 2020-08-09
Rated 4 out of 5 by from Recommend I got the SkinCeuticals sample last week and it’s awesome. I love it. May require long-term use. I will buy a formal suit. Strongly recommend this
Date published: 2020-08-09
Rated 4 out of 5 by from I really like this product I have been using discoloration defense for about two weeks now and I must say that I’m already starting to see a difference in my face. I had a few old acne scars on my chin from some hormonal acne flare ups and they are fading with daily use of this product. I’m hoping to see more of a change in the next month or so.
Date published: 2020-08-08
Rated 1 out of 5 by from Didn’t work at all I’ve been using it for 3 months now with other products to make some pigmentation go away but has been unsuccessful
Date published: 2020-08-02
Rated 5 out of 5 by from Awesome I got skinceuticals sample two weeks before and it’s awesome. I love it.. Strongly recommend this
Date published: 2020-08-01
Rated 4 out of 5 by from Fantastic I am already seeing a difference in my skin discoloration. The one spot I have is getting lighter. Thank you!
Date published: 2020-07-27
Rated 5 out of 5 by from Great product.! Have been using it for past five months and have seen remarkable improvement. Dark spots on my face have diminished to a great extent. This product has helped me gain my confidence back.!
Date published: 2020-07-22
Rated 5 out of 5 by from The best product I’ve ever used for blemishes! I bought this in September for a horrific dark spot in the center of my T-zone. No exaggeration, it started working right away. It takes forever for blemishes to disappear for me, and this was gone within a month! I used it in conjunction with a good exfoliant, and the Phyto Masque. It’s worth the price.
Date published: 2020-07-20
Rated 5 out of 5 by from Magic in a bottle! Had pigmentation from acne scars, after two months of using it (I'm bad at consistency so I applied on the area about 4x a week) and omg!!!!! if i has worn everyday im sure results would've been sooner! My dark spots are gone! All of them! Amazing!!!!!! Used it as a spot treatment, only for dark spots. MAGIC IN A BOTTLE!!!
Date published: 2020-07-16
Rated 5 out of 5 by from Good-bye spots I have age spots on my face which have been greatly reduced by the use of this serum for a couple of months. I apply it a.m. and p.m. and use SPF 55 during the day. For a topical solution this a good answer to the problem.
Date published: 2020-07-11
Rated 1 out of 5 by from Not good! I bought this product for two months ago and it didn’t work!
Date published: 2020-07-06
Rated 5 out of 5 by from Best for preventing dark spot I received a sample of this and I love it! So I purchased one in full size. It fades the old acne marks but really work best on the new spot.
Date published: 2020-06-28
Rated 5 out of 5 by from Excellent product I’m using this product for one month and I really surprise with the good result. I almost recover the original skin color of my neckline. 100% recommended
Date published: 2020-06-25
Rated 5 out of 5 by from Great serum I received a sample of this serum and was surprised at how just with 2 uses my skin looked better! Will definitely be making a purchase soon
Date published: 2020-06-24
Rated 1 out of 5 by from Don’t waste your money I just received a sample but had actually brought a full size in the past. I did not see any difference in dark spots.
Date published: 2020-06-21
Rated 4 out of 5 by from Blur effects I received a sample so I only used it for a couple of days. I noticed my pores were blurred did not notice dark spots fading but I only used it for a couple of day. I am definitely interested in purchasing a bottle to see more results.
Date published: 2020-06-20
Rated 2 out of 5 by from Not convinced.. I've used the product for over a year, and don't notice a difference. Were it less expensive I might give it another go, but having purchased two bottles, I'm not convinced it's worth it.
Date published: 2020-06-17
Rated 1 out of 5 by from Did not work I wanted this to work on my sun spots, sadly it did not. I used this product for over a year twice daily in hopes it would work. There really was no change in my stubborn sun spots. I love SkinCeuticals and have been using CE Ferulic for years. I added discoloration defense a year ago and I am really disappointed that I have had no results. I don't recommend if you have stubborn sun spots. Moving on with my quest to the next promised sun spot lightener.
Date published: 2020-06-16
Rated 1 out of 5 by from New bottle... and is dark already? I bought it and it is dark already, why? Is this normal?
Date published: 2020-05-22
Rated 5 out of 5 by from Improved coloring on my face after just a few uses I received a sample of this two weeks ago. I used it once a day in the morning after my CE serum and it’s greatly reduced my redness and evened out my skin tone. It does leave a slight tint to my skin but it just makes me look tanner so I’m not complaining!
Date published: 2020-05-13
Rated 2 out of 5 by from If your product is dark... I saw a few posts about the discoloration of this product. I received a product that was already discolored. I asked about the color and they avoided answering it. In short, they offered to replace it, reneged, and then told me they would refund the difference. (I received this in a kit). The fact that they offered to replace it tells me that once it turns dark, it is no longer effective. I have not noticed a changed in the month that I have used it. I bought another one, and it is pale-yellow, so I will see how that goes. I like the consistency, but it makes the skin tacky afterward.
Date published: 2020-05-09
Rated 1 out of 5 by from No effect Been using this morning and night (with spf during day wear) and have noticed no results. Any retinol or vitamin c serum would work way better. Expensive product for no results.
Date published: 2020-05-06
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