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Discoloration Defense Skin discoloration serum

Discoloration Defense is rated 4.0 out of 5 by 69.
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Daily dark spot corrector targets visible skin discoloration for brighter, more even-looking skin

skin types

Dry
Normal
Oily
Combination

skin condition

Discolorations

$98.00

Availability:

In Stock

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Product Details

Discoloration Defense is a layerable, daily-use dark spot corrector clinically proven to reduce the appearance of key types of skin discoloration, including hard-to-treat forms such as stubborn brown patches and post-acne marks. Formulated with 3% tranexamic acid, 1% kojic acid, 5% niacinamide, and 5% HEPES, this latest-generation formula improves the appearance of skin discoloration, brightens skin, and evens skin tone in as early as 2 weeks.

  • Features a synergistic blend of anti-discoloration ingredients to reduce the appearance of skin discoloration, improve brightness, and minimize the reoccurrence of discoloration (with continued use)
  • 60% average improvement in the appearance of stubborn brown patches
  • Paraben-, fragrance-, silicone-, gluten-, and hydroquinone-free
  • Ideal at-home complement to professional skin discoloration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations

How To Use

  • Twice daily, apply 3-5 drops of this skin discoloration serum to the face.
  • If using in the morning, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad spectrum SPF 50+ sunscreen.
  • Limit sun exposure while using this product.
  • Do not use on irritated or broken skin. If irritation occurs, discontinue use.
  • Visible Results

  • before
    after

    In a 12-week clinical study, Discoloration Defense significantly improved the appearance of key skin discoloration markers:

    • 60% average improvement in the appearance of stubborn brown patches
    • 59% average improvement in the appearance of skin discoloration
    • 81% average improvement in the appearance of post-acne marks
    • 59% average improvement in the appearance of even skin tone

    See Protocol

    Protocol: Average results shown. A 12-week, single-center, clinical study was conducted on 50 females, ages 25 to 60, Fitzpatrick I-IV, with mild to moderate facial skin discoloration, including stubborn dark spots, post-acne marks, and uneven skin tone. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.

  • Science & Proof


  • Science

    Everyday elements—including UV exposure, prescription drugs, and some professional treatments—can trigger production of melanin in the skin’s lowest epidermal layers. This excess melanin rises to the surface of the skin, causing visible skin discoloration. Discoloration can manifest in a range of ways, including post-acne marks and stubborn brown patches on the cheekbones, forehead, and upper lip.

    Discoloration Defense is the latest-generation dark spot corrector, using a combination of potent and proven anti-discoloration ingredients—including new tranexamic acid—to address key types of skin discoloration.

Key Ingredients

  • 3% Tranexamic Acid
  • 1% Kojic Acid
  • 5% Niacinamide
  • 5% HEPES

This synthetically-derived ingredient minimizes the reoccurrence of skin discoloration and stubborn brown patches with continued use.

Learn more about Tranexamic Acid

See all ingredients

Aqua / Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Tranexamic Acid, Propylene Glycol, Hydroxyethyl Urea, Kojic Acid, Caprylyl Glycol, Allantoin, Chlorphenesin, Xanthan Gum, Disodium Edta

Physician Insight

Physician image

I recommend Discoloration Defense between chemical peels- this formula targets stubborn types of discoloration but is gentle on my patients’ skin, making it ideal for an at-home regimen between treatments.

Dr. Sarah Sawyer

Learn about Dr. Sarah Sawyer

Complete Your Regimen

Reviews

Rated 5 out of 5 by from WOW! I get terrible ingrown from shaving my legs and then I have a terrible nervous habit of picking, which as led to some embarrassing scars on my legs. Many products are not always intended for use for anywhere other than the face. I bought this product to try it out on my legs. While I know that it will not completely get rid of the scaring, I have already noticed that the brown spots have faded significantly. The darker ones will need more work but I am optimistic!
Date published: 2019-08-15
Rated 5 out of 5 by from Nice Product I received the deluxe sample of this product and have loved what it's done for the evenness of my skin tone. My skin is more even and glowy. It also faded some long-lasting post-acne marks. Very pleased with this product!
Date published: 2019-08-02
Rated 1 out of 5 by from No Change I used this product as directed until the bottle was depleted along with 30 sunscreen. Sadly, I did not see any changes in my brown spots.
Date published: 2019-07-31
Rated 5 out of 5 by from Love it I have been using this twice a day for over 6 months now. My skin feels so smooth right after applying and I have seen quiet a difference in my skin!
Date published: 2019-07-28
Rated 4 out of 5 by from I Like it! So I bought this because I have hyperpigmentation and melasma. The reason why I gave it four stars is because it hasn’t really lightened any of my spots BUT it does do something I wasn’t expecting. When it is that time of the month my face gets really blotchy and uneven and it just looks bad. But this product completely stopped that! So for that definitely will be continuing to purchase!
Date published: 2019-06-26
Rated 1 out of 5 by from No change I used it till it was empty and while using it I also put sun protection on and nothing changed.
Date published: 2019-06-16
Rated 5 out of 5 by from Game Changer! This really helped my dark spots and prevent new dark spots from forming. My skin looks so good!
Date published: 2019-06-10
Rated 5 out of 5 by from Awesome Serum for Discoloration I didn't do well in terms of sunscreen reapply during my vacay so that I got a few frckles, but this serum helped me to make them less obvious! I paired this one with the PHYTO+ serum as well, and the combo made my acne redness go away faster for sure.
Date published: 2019-06-09
Rated 3 out of 5 by from Average product I haven't noticed a change in my discoloration and have been using the product for about a year. Very overpriced.
Date published: 2019-06-08
Rated 5 out of 5 by from Noticeable improvement! I have skin discoloration, brown spots. After a week of consistent use, night and day, with CE Ferulic, I see improvement.
Date published: 2019-06-08
Rated 4 out of 5 by from I like it I started using this about a year ago. I don’t know that it helped much but I do know that it helped my discoloration from getting worse. I went to Mexico this year and used this on my hands and come bad with no added discoloration.
Date published: 2019-06-08
Rated 4 out of 5 by from It Works! I've been using this product for over a year and it works for me. I have a lot of discoloration so sticking with it for the long term is important.
Date published: 2019-06-08
Rated 5 out of 5 by from Love it In the first weeks the spots are markedly reduced I love it
Date published: 2019-06-08
Rated 5 out of 5 by from Great product I tend not to use a lot of products on my face but I never miss using this AM and PM. I’ve used it for nearly a year and saw results within the first weeks. While I still have some darker areas, they have faded and have less defined edges so they blend in and are less noticeable. And, no new spots!
Date published: 2019-06-08
Rated 5 out of 5 by from Uneven skin tone beware I am in love with this product. I use it twice a day (mornings and evenings) in conjunction with a 20% vitamin C serum. Contrary to popular belief, I’ve had zero problems combining this product (which contains Niacinimide) with a vitamin C serum. This product has done an amazing job evening out my overall skin tone. My skin has never looked better. This product is a definite repurchase.
Date published: 2019-04-23
Rated 4 out of 5 by from Good Product I received this as a complimentary sample. I have been using it twice daily as directed for about 4 weeks now. I use one drop which covers the sun spot discoloration on my checks. I am just now noticing the spots have slightly faded. Really happy as I wanted to be patient but began to wonder if it was going to work. I would buy this product but will continue to wait to see how much more spots fade.
Date published: 2019-04-22
Rated 5 out of 5 by from Very pleased with this product I have been using this product for about 5 weeks and I find that it has helped fade the dark spots I have from sun exposure and has prevented any new dark spots when I do have to go out in the sun when used with a 50 SPF sunscreen
Date published: 2019-04-22
Rated 5 out of 5 by from Discoloration Defense I was given this as a sample from my dermatologist. I have freckles, used to tan regularly, and after some laser and light treatments to lessen dark spots and sun damage, I was told to incorporate this into my skincare regimen. I have sensitive skin and this product has not caused me to break out at all. I feel like in the short time I have used this product, it has helped improve my results. It layers well with the other SkinCeuticals products I have. I will continue to use this product and look forward to seeing more long lasting results in my skin's overall complexion and skin tone.
Date published: 2019-04-20
Rated 5 out of 5 by from Dark Spots no more ! I just love the Discoloration Defense ! After years in the sun I started getting dark spots and my skin tone was blotchy. How refreshing it was to see my dark spots fade away and my skin tone look so much better. Thank You SkinCeuticals for your product. ❤️
Date published: 2019-04-20
Rated 4 out of 5 by from Nothing drastic but continuing use I am three months in and I plan to continue using the product! There hasn't been any drastic changes (not that I expect the disappearance of dark spots overnight), but I am noticing an overall lightening effect on my face. The serum is colorless, odorless, and absorbs well into the skin.
Date published: 2019-04-20
Rated 5 out of 5 by from Great treatment I bought this a six months ago and it was so good to my face
Date published: 2019-04-20
Rated 5 out of 5 by from The best!!! I bought this product three months ago and it is simply the best for blemishes I have ever used! My smudges diminished noticeably. I am very happy with this purchase.
Date published: 2019-04-20
Rated 5 out of 5 by from Works!! I been used this product for a month ago, I have this very dark/texture spots , in my cheeks , nose , since a been used this product it got lighter, the process is slow ( I think is beacuse my spots are very dark) but it works . I used vitamin C, then Discoloration defense and sunblock ( everything from skinceuticals) I recommend it!
Date published: 2019-04-20
Rated 5 out of 5 by from It really works I have noticed clearer brighter skin in just a few weeks. I do use it with Metacell Renewal which is also supposed to help with my hyperpigmentation concerns. All you need is three drops.
Date published: 2019-04-19
Rated 2 out of 5 by from Not easy to see results I used one whole bottle and I did not see any results.
Date published: 2019-04-19
Rated 5 out of 5 by from Just the sample When I tell u Im not one to spend alot on face care, I will gladly spend my money with Skinceuticals! I am so grateful for this brand, Everything that I use and try I am so impressed! This product, just the sample, has lightened my dark spots in just 3 weeks, I can cry! I thank you for creating a face wash (lha cleansing gel) and this discoloration defense, together my face is flawless!
Date published: 2019-04-17
Rated 4 out of 5 by from This product makes my face brighter. I like to use it before moisturizer. Its set at an average price for what you get. Which is and average size bottle. The product goes a far ways with a little bit of use.
Date published: 2019-03-28
Rated 1 out of 5 by from No results Did not change a thing. Spots and hyperpigmentation has no change at all.
Date published: 2019-03-25
Rated 5 out of 5 by from Amazing product !!’ Received this product as a sample and used only for two weeks it works really well I can see the visible difference
Date published: 2019-03-20
Rated 5 out of 5 by from Great Product This product has done wonders for my skin. It's literally glowing. I use this in combination with the Phlorentin CF. The two together are amazing.
Date published: 2019-03-16
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