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Discoloration Regimen Set Limited edition set featuring Phloretin CF®, Discoloration Defense, and Physical Fusion UV Defense SPF 50

Discoloration Regimen Set is rated 4.3 out of 5 by 360.
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The Discoloration Regimen Set combines a patented daytime vitamin C antioxidant face serum that delivers advanced environmental protection and diminishes the appearance of fine lines and discoloration, a daily dark spot corrector that targets visible skin discoloration for brighter, more even-looking skin, and a tinted sunscreen fluid with 100% mineral filters that provides broad spectrum UVA/UVB protection, while promoting natural radiance and a more even skin tone.

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Product Details

Phloretin CF® With Ferulic acid features a patented synergistic combination of 2% Phloretin, 10% pure Vitamin C (l-ascorbic acid), and 0.5% Ferulic acid for enhanced protection against atmospheric skin aging – environmental damage and premature signs of aging caused by free radicals from UVA/UVB, and ozone pollution (O3). In addition to antioxidant protective benefits, Phloretin CF improves the appearance of discoloration, fine lines, and uneven skin tone.

  • Provides advanced environmental protection by neutralizing damaging free radicals
  • Improves the appearance of discoloration and overall skin tone
  • Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours
  • Paraben-, fragrance-, and dye-free
  • Ideal for normal, oily, and combination skin types

Discoloration Defense is a layerable, daily-use dark spot corrector clinically proven to reduce the appearance of key types of skin discoloration, including hard-to-treat forms such as stubborn brown patches and post-acne marks. Formulated with 3% Tranexamic acid, 1% Kojic acid, 5% Niacinamide, and 5% HEPES, this latest-generation formula improves the appearance of skin discoloration, brightens skin, and evens skin tone in as early as 2 weeks.

  • Features a synergistic blend of anti-discoloration ingredients to reduce the appearance of skin discoloration, improve brightness, and minimize the reoccurrence of discoloration (with continued use)
  • 60% average improvement in the appearance of stubborn brown patches
  • Paraben-, fragrance-, silicone-, gluten-, and Hydroquinone-free
  • Ideal at-home complement to professional skin discoloration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations

Physical Fusion UV Defense SPF 50 is a weightless fluid that combines 100% mineral filters with translucent color spheres for effective broad spectrum UVA/UVB protection and an even, radiant finish. This high protection Zinc oxide sunscreen also contains Artemia salina, a plankton extract known to increase skin’s resistance to UV- and heat-induced stress.

  • Sheer, tinted sunscreen adapts to most skin tones without a white cast
  • Water resistant for up to 40 minutes
  • Boosts radiance for a more even, luminous complexion
  • Helps boost skin’s natural defenses to environmental stress
  • Paraben-free and fragrance-free; non-comedogenic
  • Ideal for all skin types, even very sensitive skin

How To Use


In the morning after cleansing and toning, apply 4-5 drops of Phloretin CF® With Ferulic Acid to a dry face, neck, and chest before other skincare products. May be used on the back of the hands. Then apply 3-5 drops of Discoloration Defense to the face. Finally, apply Physical Fusion UV Defense SPF 50 liberally to the face, neck, and chest 15 minutes before sun exposure and before applying makeup. Reapply sunscreen after 40 minutes of swimming, sweating, immediately after towel drying, and at least every two hours.

Key Ingredients

  • Phloretin CF® with Ferulic Acid
  • Discoloration Defense
  • Physical Fusion UV Defense SPF 50

2% Phloretin: Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, this antioxidant neutralizes damaging free radicals, helps improve cell turnover, and improves the appearance of discoloration.

10% L-ascorbic acid: Lauded for its superior antioxidant benefits, this highly potent form of pure Vitamin C neutralizes damaging free radicals and protects against oxidative stress while providing visible anti-aging benefits.

0.5% Ferulic acid: A plant-based antioxidant, Ferulic acid neutralizes free radicals and enhances the antioxidant benefits of Phloretin and Vitamins C and E.

See all ingredients

Phloretin CF® With Ferulic Acid:
Aqua / Water / Eau, Dipropylene glycol, Alcohol denat., Ascorbic acid, Butylene glycol, Triethyl citrate, Phloretin, Ferulic acid

Discoloration Defense:
Aqua / Water, Butylene glycol, Niacinamide, Hydroxyethylpiperazine Ethane sulfonic acid, Glycerin, Tranexamic acid, Propylene glycol, Hydroxyethyl urea, Kojic acid, Caprylyl glycol, Allantoin, Chlorphenesin, Xanthan gum, Disodium edta

Physical Fusion UV Defense SPF 50:
Titanium dioxide, Zinc oxide, Water, Dimethicone, Isododecane, C12-15 alkyl benzoate, Undecane, Triethylhexanoin, Isohexadecane, Nylon-12, Caprylyl methicone, Butyloctyl salicylate, Phenethyl benzoate, Styrene/acrylates copolymer, Silica, tridecane, Dicaprylyl carbonate, Dicaprylyl ether, Talc, Dimethicone/peg-10/15 crosspolymer, Aluminum stearate, Pentylene glycol, Peg-9 polydimethylsiloxyethyl dimethicone, Alumina, Polyhydroxystearic acid, Phenoxyethanol, Magnesium sulfate, Caprylyl glycol, Iron oxides, Peg-8 laurate, Disteardimonium hectorite, Triethoxycaprylylsilane, Tocopherol, Propylene carbonate, Artemia extract, Benzoic acid, C9-15 fluoroalcohol phosphate, Peg-9


Rated 2 out of 5 by from Didn't do much after whole bottle used. I used this twice a day till the bottle was gone, didn't notice much of a difference.
Date published: 2020-10-22
Rated 1 out of 5 by from Bad product, I bought this product and is a waste of money,no change on my face dark spots
Date published: 2020-10-20
Rated 4 out of 5 by from Overall skin tone improvement I have been using this product for 2 months and along with triple lipid restore and have noticed an improvement in my overall skin tone and slightly diminished fine lines
Date published: 2020-10-19
Rated 1 out of 5 by from No noticeable difference in brown spots I have use this product 2 times a day for 2 months and unfortunately have not seen any improvement in my brown spots
Date published: 2020-10-19
Rated 1 out of 5 by from It doesn’t do anything I got a sample of this product. Although it seems promising it didn’t make a difference on my dark spots. It seems to be missing something....
Date published: 2020-10-19
Rated 1 out of 5 by from Not impressed I received a sample of Discoloration Defense and emptied the packet into a small sample jar to keep it fresh. I focused on the brown sun spots underneath both eyes, using a drop twice a day. I have also used 4% hydroquinone for several years and sunscreen every day. While the product had a pleasant texture, wasn't greasy or perfumed, it also didn't seem to make a noticeable difference in the color of the spots. Pictures in the same light don't show real change. Maybe old sun damage is just too much for Discoloration Defense. I don't think I would spend almost a hundred dollars on a bottle, if using it twice daily for 2 months made no difference at all.
Date published: 2020-10-11
Rated 5 out of 5 by from Works wonders I started using this product in addition to my CE Ferulic treatment about 3 weeks ago. My skin has improved so much that it will be a permanent addition. I have had lots of sun exposure that I thought I was stuck with the brown patches. They are barely visible now.
Date published: 2020-10-04
Rated 2 out of 5 by from Disappointed I've been using this product faithfully every day for 3 months. I've used sunscreen every day and have super careful about wearing a hat to keep the sun off my face. I haven't noticed any difference in fine lines, and my discoloration has actually gotten worse. Won't be purchasing this again.
Date published: 2020-10-02
Rated 4 out of 5 by from Feels good on skin I was lucky enough to receive 2 sample packets of this serum. A little goes a long way and I was able to use those packets morning and night for two months. I have a dark spot on my cheek that is a bit large. As far as I can tell, the spot has not changed much. It might be a little lighter, but it is still there. However, I did notice a difference on the quality of my skin. It looks smoother (not so much wrinkles, but pores). It is a pleasant part of my daily routine. I like the consistent. Not oily or heavy and quickly absorbed by skin. I didn't experience any adverse reactions.
Date published: 2020-09-28
Rated 4 out of 5 by from Great! This product truly improves the appearance of brown spots and hyperpigmentation from old acne.
Date published: 2020-09-27
Rated 5 out of 5 by from Great product, but I think it oxidized? I absolutely love this product. It has been such a game changer for my hyper-pigmentation. However, the serum has turned to a dark orange/brown. Can I still use it?
Date published: 2020-09-15
Rated 1 out of 5 by from Don’t waste your money I bought this to lighten my ugly moles and I’ve been using for a week and there is no change at all. I’ve been trying to get rid of my moles from the sun forever. I’m hopeless now.
Date published: 2020-09-08
Rated 5 out of 5 by from Ok people, I'm a believer This actually works. Im not paid to write fact quite the opposite, I paid a truck load of money for this ha. I have Mediterranean skin and two dark spots on each of my cheeks. Trying to avoid IPL, I use an exfoliating cloth to scrub any dead skin cells and use these two products plus SPF they gave as a free gift. Yeah a difference. They are not gone but 50% lighter. Probably will be 35-40% in the end and then maybe a few IPL's. Regardless, SkinCeuticals is legit and these two products do help. I will add you need to be diligent. None of this when you remember business. No do it morning and night. Also as a tip that maybe everybody knows and I'm the last to the party, but tilt your head back and drop it directly on your face ...gently mind you. The finger transfer is a mess.
Date published: 2020-09-06
Rated 2 out of 5 by from No improvement I've tried many skinceuticals products and some work for my skin and others don't. This on. unfortunately has not at all after using the full bottle. I will go back to Phyto for discoloration which has worked better for me.
Date published: 2020-09-05
Rated 5 out of 5 by from Effective. Received a sample with a order and found it very effective. Absorbs quickly, has no smell (yay!), and I saw results faster than expected. Ordered more before sample was gone. Now a staple in my skin care. Impressed.
Date published: 2020-08-28
Rated 3 out of 5 by from Sample I wish I could give review on the sample product I received. But when I opened the sample packet. It spilled out all over my hand. I can not give you an honest opinion on the product I received except the packaging needs to be improved. But in the past I have used several of Skinceuticals products. I have always been pleased with the results of other products.
Date published: 2020-08-21
Rated 3 out of 5 by from Not effective after less than 3 months I’m extremely disappointed that I paid so much for this product. I tried to be conservative with it to make it last, but it hasn’t even been three months and the serum has turned brown and smells like rotten eggs. I was told it’s not effective once it turns brown. This is so frustrating because the product is great and really improved my skin before it went bad.
Date published: 2020-08-20
Rated 1 out of 5 by from Discoloration Defense I received a sample packet of this when I cut and tried to squeeze out a small amount all of the serum squirted out. Company has to figure out how to better package a sample. I have been using the A.G.E Interrupter for the face for six weeks with no results so I am not purchasing this. These products are not cheap I expect a usable sample and results will not purchase any products in the future.
Date published: 2020-08-17
Rated 5 out of 5 by from I love all skinceuticals products. This one is def a top fav. I use this right after I tone and it has improved my skin. Im still in the middle of using it so cant tell about the full strength of it. It is very pricey though.
Date published: 2020-08-17
Rated 5 out of 5 by from Amazing product This was recommended by our dermatologist for treating pigmentation and after 1 month, we can see the pigmentation has faded quite a bit already.
Date published: 2020-08-16
Rated 1 out of 5 by from Review There wasn't enough on that sample sheet to be able to tell a difference.
Date published: 2020-08-09
Rated 4 out of 5 by from Recommend I got the SkinCeuticals sample last week and it’s awesome. I love it. May require long-term use. I will buy a formal suit. Strongly recommend this
Date published: 2020-08-09
Rated 4 out of 5 by from I really like this product I have been using discoloration defense for about two weeks now and I must say that I’m already starting to see a difference in my face. I had a few old acne scars on my chin from some hormonal acne flare ups and they are fading with daily use of this product. I’m hoping to see more of a change in the next month or so.
Date published: 2020-08-08
Rated 1 out of 5 by from Didn’t work at all I’ve been using it for 3 months now with other products to make some pigmentation go away but has been unsuccessful
Date published: 2020-08-02
Rated 5 out of 5 by from Awesome I got skinceuticals sample two weeks before and it’s awesome. I love it.. Strongly recommend this
Date published: 2020-08-01
Rated 5 out of 5 by from WORTH IT I have struggled with acne, scarring, and discoloration for years. I have tried SO many products professional and drug-store brands and have never found anything as amazing as Phloretin CF. It is 100% worth the money. I received a sample of it after buying the LHA cleanser, and just from using that sample my skin had already started to change significantly. I gave in and bought the full size bottle and will continue to do so. I feel confident when I'm not wearing makeup, and honestly don't even have to wear much make up now. Highly recommend this product. It is a staple in my routine now along with the LHA Cleanser.
Date published: 2020-07-30
Rated 5 out of 5 by from I just started using this serum and I love it! It does have a strong smell, as most vitamin c serums do. It sinks into my skin and so far my super sensitive skin loves it. Combine this with other skinceuticals products and your skin will be amazing.
Date published: 2020-07-30
Rated 5 out of 5 by from Totally Worth It I'm 38, fair, with mild acne roseacea. Not only does this give my skin a youthful glow but after a mild purging of a week or so, my acne and any bumps are almost completely gone, redness reduced, and I have a softer, more even complexion overall. Most 'actives' are too harsh for me and the CE Ferulic broke me out. So glad I tried this one. It's expensive but its the only product that's made such a noticeable difference in my skin.
Date published: 2020-07-30
Rated 4 out of 5 by from Fantastic I am already seeing a difference in my skin discoloration. The one spot I have is getting lighter. Thank you!
Date published: 2020-07-27
Rated 4 out of 5 by from Great antioxidant! I will say I didn’t give this 5 stars because I don’t love how watery the consistency is. I prefer the gel version, as it is easier to move across the skin without wasting too much of the product.
Date published: 2020-07-24
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