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Glow Regimen Set Limited edition set featuring Metacell Renewal B3, Glycolic 10 Renew Overnight, and Retexturing Activator

Glow Regimen Set is rated 4.7 out of 5 by 238.
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The Glow Regimen Set combines a daily emulsion formulated to improve the appearance of early signs of aging, a nighttime glycolic acid cream with a true 10% Glycolic acid value to promote cellular turnover for healthy, glowing skin, and an oil-free serum to exfoliate skin and replenish moisture for radiant, smooth skin.

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Product Details

Metacell Renewal B3 utilizes a patent-pending aqueous emulsion to deliver a high concentration of 5% Niacinamide (vitamin B3) combined with a firming Tripeptide concentrate, and 15% pure Glycerin to address early signs of photoaging. While signs of photoaging appear at different intensities according to skin biology, lifestyle, geography, sun protection behavior, and skincare regimen, they have a multiplicative effect, creating a prematurely-aged appearance. This comprehensive daily emulsion visibly improves these early signs of photoaging by increasing cell turnover to resurface skin, help reclarify and even skin tone, and improve the appearance of wrinkles and surface elasticity.

  • Promotes skin renewal by increasing cell turnover
  • Strengthens skin’s moisture barrier
  • Reduces the appearance of discoloration and blotchiness
  • Lightweight emulsion delivers intense hydration without a heavy or tacky feel
  • Helps improve the appearance of skin’s firmness

Glycolic 10 Renew Overnight is formulated with a free acid value of 10% Glycolic acid, allowing it to work at a true 10% concentration proven optimal in promoting effective exfoliation and natural cell turnover. Free acid value refers to the true strength of a Glycolic acid product, and is affected by both the concentration of acid and the pH of the formula. This potent night cream is synergistically blended with 2% Phytic acid to promote skin clarity and brightness, and a triple action-soothing complex to help support the skin barrier. Proven tolerable for nightly use, Glycolic 10 Renew Overnight improves the appearance of skin texture and tone to promote a bright complexion and glowing skin.

  • Features a free acid value of 10% Glycolic acid to promote cellular turnover
  • 36% average improvement in glowing skin
  • Dye- and fragrance-free
  • Tested tolerable for nightly use
  • Ideal complement to chemical peels to pre-condition skin and extend results; always consult with a physician for individual regimen recommendations

Retexturing Activator is a revolutionary replenishing and resurfacing serum that helps reinforce the skin’s barrier for healthier, more radiant skin. Using patented technology, this unique serum is highly effective in promoting proper exfoliation while optimizing the skin’s amino acid supply to reinforce the external barrier. Formulated in an efficient oil-free delivery system suitable for all skin types to replenish and exfoliate skin for noticeably soft, smooth skin texture. This oil-free serum has the resurfacing power of daily 20% Glycolic acid treatment.

  • Bi-functional exfoliation and hydration
  • Diminishes the appearance of surface lines and smoothes skin
  • Increases the look of overall radiance
  • Balances moisture levels
  • Ideal for all skin types
  • Stimulates enzymes that help break the bonds that bind dead cells to the surface of the skin, to diminish surface lines and wrinkles

How To Use


Twice daily, apply 4-6 drops of Retexturing Activator to the face, neck, and chest.

In the evening, shake Glycolic 10 Renew Overnight before use. Some skin types may require time to acclimate to Glycolic acid. In these cases, precondition skin for this night cream by limiting initial use to once every other evening. Avoiding the eye area, apply an even, pea-sized layer over entire face and neck. After one week, increase to every evening or as advised by a skincare professional. With use of a high-concentration Glycolic acid, it is common to experience mild symptoms of skin detoxification such as redness and temporary skin purging. Generally, these side effects resolve with continual use.

Twice daily, massage 1-2 pumps of Metacell Renewal B3 into a thin, even layer onto the entire face, neck, and chest.

Key Ingredients

  • Metacell Renewal B3
  • Glycolic 10 Renew Overnight
  • Retexturing Activator

5% Niacinamide (vitamin B3): Helps reduce the appearance of skin discoloration and strengthens skin’s moisture barrier.

2.5% Firming tri-peptide concentrate: A blend of powerful peptides helps reduce the look of fine lines, and improves the appearance of firmness.

15% Pure glycerin: This humectant has water-binding properties that deliver intense hydration without a heavy or tacky feel.

See all ingredients

Metacell Renewal B3:
Aqua / water / eau, glycerin, Dimethicone, Niacinamide, Propanediol, Dimethicone/peg-10/15 crosspolymer, Methylsilanol/silicate crosspolymer, Sodium chloride, Polymethylsilsesquioxane, Phenoxyethanol, Microcrystalline cellulose, Ci 77163 / bismuth oxychloride, Chlorphenesin, Caprylyl glycol, Sodium citrate, Ethylhexyl hydroxystearate, Peg-10 dimethicone, Disodium edta, Cellulose gum, Laminaria digitata extract, Adenosine, Citrus aurantium amara flower oil / bitter orange flower oil, Melaleuca viridiflora leaf oil, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, Linalool, Cymbopogon flexuosus oil, Citral, Limonene, Pelargonium graveolens flower oil

Glycolic 10 Renew Overnight:
Aqua/ water, Glycolic acid, Dicaprylyl carbonate, Dimethicone, Sodium hydroxide, Butylene glycol, Propanediol, Glycerin, Phytic acid, Cetyl Peg/Ppg-10/1 dimethicone, Aluminum starch octenylsuccinate, Nylon-12, Poly-Glyceryl-4 isostearate, Magnesium sulfate, Jojoba esters, Phenoxyethanol, Helianthus annuus seed cera/Sunflower seed wax, Caprylyl glycol, Disodium edta, Salicylic acid, Acacia decurrens flower cera/Accia decurrens flower wax, Polyglycerin-3, Tocopherol, Pentaerythrityl tetra-di-T-butyl hydroxyhydrocinnamate

Retexturing Activator:
Aqua / water / eau, Hydroxyethyl urea, Hydroxyethylpiperazine ethane sulfonic acid, Pentylene glycol, Saccharomyces/ Xylinum / Black tea ferment, Glycerin, Sodium hyaluronate, Methylparaben, Phenoxyethanol


Rated 5 out of 5 by from My favorite serum EVER The Retexturing Activator is a desert-island product for me! (If I could only take one product with me, this is hands-down the winner!) I have moderate eczema, and this keeps my skin smooth and healthy far more effectively than any of the prescriptions my dermatologist has had me try. My skin actually stays hydrated and smooth instead of flaking off. (That’s completely amazing after years, literally, of my skin peeling every week.) I don’t really believe in miracle serums, or in products that promise to solve all your skin complaints with one formula. But this serum is by far the best skincare product I have ever used, and the effects on my skin are truly amazing. I would honestly recommend that if you’re on the fence, you give this one a try — I’m incredibly happy that I did!
Date published: 2020-10-21
Rated 5 out of 5 by from Love it This serum is amazing. I watched on the skinceuticals instagram live chats with one of the dermatologists saying women in their 30's need to start using the metacell renewal as prevention. I purchased it right after and am so pleased with the product. It is a mixture of a serum and a moisturizer so it's light weight and doesn't feel heavy on your skin. My skin is instantly brighter and more even looking. My skin has really taken a hit turning 30 with adult acne+mascne from wearing a mask to work 12+ hours/day 5 days a week. I decided to try Skinceuticals and it's changed my life for the better. I have used the gentle cleanser+vitamin C+phytocorrective+metacell+spf every morning for the last month and my skin glows. I highly recommend you try this product/line, it's really helped my skin.
Date published: 2020-10-06
Rated 4 out of 5 by from It’s amazing I have been using this product for about a month now and I love it. It is a bit strong for my skin and can dry it out and make it red and irritated. But I just switched to using it every other day and it’s not making it dry any more. It looks youthful and dewy. I’m definitely a fan and am on the program to get it every 2 months.
Date published: 2020-10-05
Rated 4 out of 5 by from Love the product but needs better packaging! I bought this back in June to help with sunspots, anti-aging and moisture now that I’m in my late twenties. I move how smooth the product is and it’s not heavy at all. It has helped make my skin glow. One downside is the packaging. I thought I was finished with the bottle since nothing was coming out of the pump. But after 5 minutes of struggling to open the bottle I realized there was a clog in the giant tube they put inside. I had even ordered more. Be careful if you throw away your bottles without opening them! It’s worth the struggle. Can’t let this stuff go to waste!!
Date published: 2020-09-22
Rated 5 out of 5 by from Hydrating! The best products hands down for use while on Retin A. This solved all my dry skin problems while not clogging my pores. Miracle serum! Word every penny. I have tried everything, look no further.
Date published: 2020-09-21
Rated 5 out of 5 by from Life changing! I have tried everything in the book to control my adult hormonal acne, smooth out my texture, etc. I recently discovered some sun spots on my face, and this was recommended by the girl who does my injections- she said this will get rid of any spots/hyperpigmentation quickly. And, she was right. in 2.5 months of use (almost every night, following by Skinceuticals moisturizer) my spots have faded drastically! The ones on my nose are basically gone. It has also helped the stubborn blackheads on my nose - they're almost nonexistent now. This product is magic in a bottle. Totally worth the money. I am a customer for life! It works way better than my Skinmedica retinol, which is not cheap. Do yourself an amazing favor, and buy this stuff!!!
Date published: 2020-09-04
Rated 5 out of 5 by from This is witchcraft, I highly recommend!!! I have fair, slightly dry, sensitive skin with concerns about color correction/ hyperpigmentation and occasional hormonal acne usually around my chin. I received a small sample of this from my esthetician and used it for 4 days, one pump morning and night. In that short amount of time, it completely cleared up the few tiny zits on my chin and evened out all my redness. I immediately purchased the full size product. Since using this for over about two months now, my skin has never looked so even and felt so consistently moisturized. I still suffer from occasional hormonal break outs, but they clear up in a third of the time they usually would without drying out my skin. As a bonus, the texture acts almost like a primer under makeup. While the price may seem a bit daunting, the full size product should give you 4-6mos of everyday use.
Date published: 2020-09-02
Rated 3 out of 5 by from Loved the product for the first few months but... I absolutely love this product and what it does for my skin! I’m oily/acne prone and it seriously clears up my skin by only using twice a week. BUT! I hate this packaging. It leaks, you lose product, and I feel that after owning for only 3 months the product is now bad! I keep it as tight as possible and store it correctly but no matter how hard I shake it up the product won’t some to mix and become homogeneous. Not sure if i want to continue use with this issue.
Date published: 2020-08-26
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