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Glow Regimen Set Limited edition set featuring Metacell Renewal B3, Glycolic 10 Renew Overnight, and Retexturing Activator

Glow Regimen Set is rated 4.6 out of 5 by 244.
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The Glow Regimen Set combines a daily emulsion formulated to improve the appearance of early signs of aging, a nighttime glycolic acid cream with a true 10% Glycolic acid value to promote cellular turnover for healthy, glowing skin, and an oil-free serum to exfoliate skin and replenish moisture for radiant, smooth skin.

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Product Details

Metacell Renewal B3 utilizes a patent-pending aqueous emulsion to deliver a high concentration of 5% Niacinamide (vitamin B3) combined with a firming Tripeptide concentrate, and 15% pure Glycerin to address early signs of photoaging. While signs of photoaging appear at different intensities according to skin biology, lifestyle, geography, sun protection behavior, and skincare regimen, they have a multiplicative effect, creating a prematurely-aged appearance. This comprehensive daily emulsion visibly improves these early signs of photoaging by increasing cell turnover to resurface skin, help reclarify and even skin tone, and improve the appearance of wrinkles and surface elasticity.

  • Promotes skin renewal by increasing cell turnover
  • Strengthens skin’s moisture barrier
  • Reduces the appearance of discoloration and blotchiness
  • Lightweight emulsion delivers intense hydration without a heavy or tacky feel
  • Helps improve the appearance of skin’s firmness

Glycolic 10 Renew Overnight is formulated with a free acid value of 10% Glycolic acid, allowing it to work at a true 10% concentration proven optimal in promoting effective exfoliation and natural cell turnover. Free acid value refers to the true strength of a Glycolic acid product, and is affected by both the concentration of acid and the pH of the formula. This potent night cream is synergistically blended with 2% Phytic acid to promote skin clarity and brightness, and a triple action-soothing complex to help support the skin barrier. Proven tolerable for nightly use, Glycolic 10 Renew Overnight improves the appearance of skin texture and tone to promote a bright complexion and glowing skin.

  • Features a free acid value of 10% Glycolic acid to promote cellular turnover
  • 36% average improvement in glowing skin
  • Dye- and fragrance-free
  • Tested tolerable for nightly use
  • Ideal complement to chemical peels to pre-condition skin and extend results; always consult with a physician for individual regimen recommendations

Retexturing Activator is a revolutionary replenishing and resurfacing serum that helps reinforce the skin’s barrier for healthier, more radiant skin. Using patented technology, this unique serum is highly effective in promoting proper exfoliation while optimizing the skin’s amino acid supply to reinforce the external barrier. Formulated in an efficient oil-free delivery system suitable for all skin types to replenish and exfoliate skin for noticeably soft, smooth skin texture. This oil-free serum has the resurfacing power of daily 20% Glycolic acid treatment.

  • Bi-functional exfoliation and hydration
  • Diminishes the appearance of surface lines and smoothes skin
  • Increases the look of overall radiance
  • Balances moisture levels
  • Ideal for all skin types
  • Stimulates enzymes that help break the bonds that bind dead cells to the surface of the skin, to diminish surface lines and wrinkles

How To Use


Twice daily, apply 4-6 drops of Retexturing Activator to the face, neck, and chest.

In the evening, shake Glycolic 10 Renew Overnight before use. Some skin types may require time to acclimate to Glycolic acid. In these cases, precondition skin for this night cream by limiting initial use to once every other evening. Avoiding the eye area, apply an even, pea-sized layer over entire face and neck. After one week, increase to every evening or as advised by a skincare professional. With use of a high-concentration Glycolic acid, it is common to experience mild symptoms of skin detoxification such as redness and temporary skin purging. Generally, these side effects resolve with continual use.

Twice daily, massage 1-2 pumps of Metacell Renewal B3 into a thin, even layer onto the entire face, neck, and chest.

Key Ingredients

  • Metacell Renewal B3
  • Glycolic 10 Renew Overnight
  • Retexturing Activator

5% Niacinamide (vitamin B3): Helps reduce the appearance of skin discoloration and strengthens skin’s moisture barrier.

2.5% Firming tri-peptide concentrate: A blend of powerful peptides helps reduce the look of fine lines, and improves the appearance of firmness.

15% Pure glycerin: This humectant has water-binding properties that deliver intense hydration without a heavy or tacky feel.

See all ingredients

Metacell Renewal B3:
Aqua / water / eau, glycerin, Dimethicone, Niacinamide, Propanediol, Dimethicone/peg-10/15 crosspolymer, Methylsilanol/silicate crosspolymer, Sodium chloride, Polymethylsilsesquioxane, Phenoxyethanol, Microcrystalline cellulose, Ci 77163 / bismuth oxychloride, Chlorphenesin, Caprylyl glycol, Sodium citrate, Ethylhexyl hydroxystearate, Peg-10 dimethicone, Disodium edta, Cellulose gum, Laminaria digitata extract, Adenosine, Citrus aurantium amara flower oil / bitter orange flower oil, Melaleuca viridiflora leaf oil, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, Linalool, Cymbopogon flexuosus oil, Citral, Limonene, Pelargonium graveolens flower oil

Glycolic 10 Renew Overnight:
Aqua/ water, Glycolic acid, Dicaprylyl carbonate, Dimethicone, Sodium hydroxide, Butylene glycol, Propanediol, Glycerin, Phytic acid, Cetyl Peg/Ppg-10/1 dimethicone, Aluminum starch octenylsuccinate, Nylon-12, Poly-Glyceryl-4 isostearate, Magnesium sulfate, Jojoba esters, Phenoxyethanol, Helianthus annuus seed cera/Sunflower seed wax, Caprylyl glycol, Disodium edta, Salicylic acid, Acacia decurrens flower cera/Accia decurrens flower wax, Polyglycerin-3, Tocopherol, Pentaerythrityl tetra-di-T-butyl hydroxyhydrocinnamate

Retexturing Activator:
Aqua / water / eau, Hydroxyethyl urea, Hydroxyethylpiperazine ethane sulfonic acid, Pentylene glycol, Saccharomyces/ Xylinum / Black tea ferment, Glycerin, Sodium hyaluronate, Methylparaben, Phenoxyethanol


Rated 4 out of 5 by from It’s amazing I have been using this product for about a month now and I love it. It is a bit strong for my skin and can dry it out and make it red and irritated. But I just switched to using it every other day and it’s not making it dry any more. It looks youthful and dewy. I’m definitely a fan and am on the program to get it every 2 months.
Date published: 2020-10-05
Rated 4 out of 5 by from Love the product but needs better packaging! I bought this back in June to help with sunspots, anti-aging and moisture now that I’m in my late twenties. I move how smooth the product is and it’s not heavy at all. It has helped make my skin glow. One downside is the packaging. I thought I was finished with the bottle since nothing was coming out of the pump. But after 5 minutes of struggling to open the bottle I realized there was a clog in the giant tube they put inside. I had even ordered more. Be careful if you throw away your bottles without opening them! It’s worth the struggle. Can’t let this stuff go to waste!!
Date published: 2020-09-22
Rated 5 out of 5 by from Hydrating! The best products hands down for use while on Retin A. This solved all my dry skin problems while not clogging my pores. Miracle serum! Word every penny. I have tried everything, look no further.
Date published: 2020-09-21
Rated 5 out of 5 by from Life changing! I have tried everything in the book to control my adult hormonal acne, smooth out my texture, etc. I recently discovered some sun spots on my face, and this was recommended by the girl who does my injections- she said this will get rid of any spots/hyperpigmentation quickly. And, she was right. in 2.5 months of use (almost every night, following by Skinceuticals moisturizer) my spots have faded drastically! The ones on my nose are basically gone. It has also helped the stubborn blackheads on my nose - they're almost nonexistent now. This product is magic in a bottle. Totally worth the money. I am a customer for life! It works way better than my Skinmedica retinol, which is not cheap. Do yourself an amazing favor, and buy this stuff!!!
Date published: 2020-09-04
Rated 5 out of 5 by from This is witchcraft, I highly recommend!!! I have fair, slightly dry, sensitive skin with concerns about color correction/ hyperpigmentation and occasional hormonal acne usually around my chin. I received a small sample of this from my esthetician and used it for 4 days, one pump morning and night. In that short amount of time, it completely cleared up the few tiny zits on my chin and evened out all my redness. I immediately purchased the full size product. Since using this for over about two months now, my skin has never looked so even and felt so consistently moisturized. I still suffer from occasional hormonal break outs, but they clear up in a third of the time they usually would without drying out my skin. As a bonus, the texture acts almost like a primer under makeup. While the price may seem a bit daunting, the full size product should give you 4-6mos of everyday use.
Date published: 2020-09-02
Rated 3 out of 5 by from Loved the product for the first few months but... I absolutely love this product and what it does for my skin! I’m oily/acne prone and it seriously clears up my skin by only using twice a week. BUT! I hate this packaging. It leaks, you lose product, and I feel that after owning for only 3 months the product is now bad! I keep it as tight as possible and store it correctly but no matter how hard I shake it up the product won’t some to mix and become homogeneous. Not sure if i want to continue use with this issue.
Date published: 2020-08-26
Rated 5 out of 5 by from Love the product but did you change the consisten? I love this product. It works so well on my skin as it clear out all the blemish and makes my skin glow! But i notice small difference in the consistency of the product, before it was a liquid, quite thin and tended to seperate. I always had to shake it really well. The most recent one is more like a lotion, thicker and does not seperate anymore. Just wonder if Skinceuticals had changed the formula recently? Anyway, i love the new consistency;)
Date published: 2020-08-23
Rated 3 out of 5 by from Could be better! I generally like this product and what it does for night but the packaging is not ideal. It leaks out and agree seems not to maintain the homogeneity.
Date published: 2020-08-17
Rated 4 out of 5 by from I love this as a hydrating serum that doesn't break me out. However, this does not produce any significant results in the texture of my skin. It works for what it is but is overpriced for the effect in my opinion. SkinCeuticals Retexturing Activator
Date published: 2020-08-05
Rated 4 out of 5 by from Really like this serum. It does feel a little sticky but I just make sure I rub it in well. I found that this helped with the texture of my skin and pore size. I use this in my routine when I notice I get acne flare ups. I use this both in the morning and at night under my moisturizer. I will repurchase this product again.
Date published: 2020-07-26
Rated 3 out of 5 by from this is a good product for anyone who is more acne prone or has acne scarring. very effective but at a super high price point.
Date published: 2020-07-24
Rated 5 out of 5 by from So I’ve never been good at keeping up with my face but when I do use this everyday twice a day I do see a huge difference in my face and it skin tone evening out and I mix this with my age and defense drops from skinceuticles I really like this and the packaging is nice as well. Def recommend!
Date published: 2020-07-23
Rated 5 out of 5 by from One of my favourite skinceuticals serums. It’s very gentle, doesn’t burn and spreads very well. A little goes a long way. I layer this under the HA intensifier for hydrated, plump skin.
Date published: 2020-07-21
Rated 1 out of 5 by from Really Bummed with the Quality This product was great at first. After a couple months, it turned into a really thin clear liquid with little white specs coming out. It completely changed in consistency and I'm not really confortable using it on my skin. I contacted customer support and after recieving really slow responses (via chat), they told me I should have used ALL of it within three months and they can't do anything to help me. There aren't any labels on the bottle stating that it should be used within three months, and in all honesty, my skin would be way too sensitive to use this more than 2-3 times per week. I'm really surprised with the low quality of customer service for such an expensive product. I was such a big skinceuticals fan before this experience, and I wouldn't recommend using this product if you're not using it daily.
Date published: 2020-07-16
Rated 5 out of 5 by from Splendiforous! This was the first SC product that I added to my skincare routine, and what a welcome addition. It changed how I thought about product and how much I used. With Metacell I use just 1 - 2 pumps in the morning. It looks like a tiny amount but it spreads beautifully and hydrates. In the past, I had always thought that more is better and ended up with layers of heavy product. The SC lineup is lovely as it allows you to just use a bit of product and have a very effective and efficient delivery of product. It feels good and skin looks renewed. My skin tends to be very reactive/sensitive so I like to use Metacell in the evening right before putting on my retinol 0.3. This combination has reduced redness and helped me use the retinol more frequently.
Date published: 2020-07-15
Rated 5 out of 5 by from Love this product it really hydrates the skin and fixes up dull spots on your face. I highly recommend this product for all sin types and to have amazing results
Date published: 2020-07-15
Rated 5 out of 5 by from This serum is 10000% recommended you will see results in your skin in the first week of used
Date published: 2020-07-02
Rated 5 out of 5 by from 10/10 recommend. This stuff is amazing! This has helped a lot with the texture that my skin has developed due to acne, and has helped with scarring. It is 100% worth every penny, this stuff is amazing!
Date published: 2020-06-28
Rated 5 out of 5 by from Please don’t discontinue the Renew Overnight Dry LOVE the Renew Overnight Dry and it is less expensive...
Date published: 2020-06-27
Rated 5 out of 5 by from I love this ! I loved this from the first night I used it. I thought I had a sensitive skin type because I am a fair red head but I had not problem with this at all. It leaves your skin so smooth and moisturized. I started to use this and the Vit.C serum about one month ago and I have a whole new face! I'm not even 1/2 through the products and am planning when to reorder. I don't want to be with out!
Date published: 2020-06-12
Rated 1 out of 5 by from poor product I got this product as a gift, I'm a faithful user of SkinCeuticals skincare (20 plus years). The product is very thin, comes out fast, you can't control the amount that comes out.
Date published: 2020-05-30
Rated 5 out of 5 by from Brightens and glows I had some samples and loved them so much I got the full size. I first noticed after about a week of nightly usage that my skin was pretty luminous and smooth (pores smaller, less fine lines), very hydrated, and my hyperpigmentation spots have gotten lighter (I am Asian and tend to hyperpigment). I have found that I don’t need moisturizer because this makes my skin moisturized and glowing. My question for Skinceuticals - do you still recommend a moisturizer afterward or can I skip if this feels as effective as a traditional moisturizer?
Date published: 2020-05-28
Rated 5 out of 5 by from A must in your beauty regimen! I was on the hunt for a overnight cream and boy did I find it! Instructions are to use nightly which you certainly can but honestly every other day is just as good and will help stretch out the product. Worth every penny regardless immediately save overall skin improvement and tightness! Highly recommended product!
Date published: 2020-05-27
Rated 5 out of 5 by from I love this product. It smooths the skin without the irritation that can come from products like glycolic acid. I use it under my moisturizer in the morning. My boyfriend also loves this product. He uses it as an aftershave and also love how it makes his skin feel after shaving. The only bad thing is that now that he loves it my bottles go a lot quicker!
Date published: 2020-05-22
Rated 4 out of 5 by from Packaging issues I haven't been using it for too long yet but I can tell that a lot of people are having the same issue as I do, the packaging. What I did is that I changed it to a dropper one and now it works so much better. I hope this can help you all and maybe in the future the brand will fix this problem.
Date published: 2020-05-19
Rated 5 out of 5 by from Fast Results! I had read a review over on the SkinCeuticals retexturing activator product where a reviewer said her dermatologist suggested to build up the usage of using first the Retexturing activator and second the glycolic 10 product at night. Well props to the review and her dermatologist. FANTASTIC results - skin is brighter, more refreshed looking, pores are smaller, and my skin is no longer dry like the Sahara Dessert! Literally I have struggled with the driest of dry skin. Not any more. I use it every night and don’t have any issues like you see with using a retinol.
Date published: 2020-05-18
Rated 4 out of 5 by from Skin care is very important to me so when I went for my first skinceuticals facial last year in Montreal I was so impressed with this product. My skin is looking great.
Date published: 2020-05-16
Rated 5 out of 5 by from Real results. I am in love with this product. I have been using this product for two years now, applying it morning and evening after washing my face with Simply Clean (2x a day) and Micro-exfoliating Scrub (every 2-3 days). Within the first two weeks of trying this product, I noticed significant improvement in my skin. My skin was usually either too dry or too oily and this made my skin feel smooth and hydrated without that greasy feel or shine. The redness and discoloration that I typically experienced in my fair-skinned face went away completely. Also, I haven't experienced hardly any acne since using this product. I LOVE THIS PRODUCT and plan on being a lifetime user.
Date published: 2020-05-14
Rated 5 out of 5 by from Love this! I received this as a sample and loved it so I purchased the full size. My skin is combination, dryer forehead and slightly oily chin and slight breakout around chin and mouth. This makes my skin smooth and bright when I wake up in the morning. Has not irritated me at all. I use Skinceuticals cleanser, toner and moisturizers already and this is my first anti-aging product and I love it.
Date published: 2020-05-07
Rated 5 out of 5 by from This is amazing I have only been using this for 1 week- about 4 drops at nighttime only- and it has already transformed my skin. I have always had dry skin, but I'm 44 now and have an autoimmune condition that makes it even worse, and I had resigned myself that the skin on my face would just have to feel rough, and completely devoid of moisture. But using this, my skin now feels normal and smooth, and when I first wake up it's even I dare say a bit dewey. I can't wait to find out what benefits will come over time! Completely worth the price.
Date published: 2020-05-02
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