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Phloretin CF® with Ferulic Acid Vitamin C serum for face

Phloretin CF® with Ferulic Acid is rated 4.6 out of 5 by 174.
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A patented daytime vitamin c antioxidant face serum that delivers advanced environmental protection and diminishes the appearance of fine lines and discoloration. U.S. Patent No. 9,248,082.

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Product Details

Phloretin CF features a patented synergistic combination of 2% phloretin, 10% pure vitamin C (l-ascorbic acid), and 0.5% ferulic acid for enhanced protection against atmospheric skin aging – environmental damage and premature signs of aging caused by free radicals from UVA/UVB, infrared radiation (IRA), and ozone pollution (O3). In addition to antioxidant protective benefits, Phloretin CF improves the appearance of discoloration, fine lines, and uneven skin tone.

  • Provides advanced environmental protection by neutralizing damaging free radicals
  • Improves the appearance of discoloration and overall skin tone
  • Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours
  • Paraben-, fragrance-, and dye-free
  • Ideal for normal, oily, and combination skin types

How To Use

In the morning after cleansing and toning, apply 4-5 drops to a dry face, neck, and chest before other skincare products. May be used on the back of the hands. It is normal for vitamin C products to darken after opening due to air and light exposure. The formula will remain effective. Once opened, it is recommended to be used within 3 months of opening.

Complete your regimen with a SkinCeuticals sunscreen. When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide the most complete protection against visible aging caused by environmental aggressors.

  • Science & Proof

  • Science

    SkinCeuticals research shows that specific combinations of antioxidants, when effectively formulated, provide superior results to each single antioxidant formulation.

    Phloretin CF is a triple antioxidant cocktail formulation shown to provide broad-range environmental protection due to a synergistic combination of 2% phloretin, 10% pure vitamin C (L-ascorbic acid), and 0.5% ferulic acid. It is formulated under the Duke Antioxidant patent. Vitamin C is a highly-potent antioxidant that is, by its structure, difficult to effectively deliver on skin. The Duke Antioxidant patent describes the formulation parameters required for effective delivery of vitamin C to skin: 1) pure l-ascorbic acid (vitamin C); 2) an acidic pH within the 2.0-3.5 pH range and; 3) a concentration between 10%-20%. SkinCeuticals is the only brand to formulate antioxidants according to these parameters.


    SkinCeuticals defines atmospheric aging as the visible result of a range of environmental aggressors on skin, including UV, infrared radiation (IRA), and pollution. Ongoing SkinCeuticals research shows that over-exposure to these aggressors may cause visible skin aging, and topical antioxidants can help prevent the impact to skin.

    Learn more about atmospheric aging and ozone pollution

Key Ingredients

  • 2% phloretin
  • 10% L-ascorbic acid
  • 0.5% ferulic acid

Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, this antioxidant neutralizes damaging free radicals, helps improve cell turnover, and improves the appearance of discoloration

Learn more about phloretin

See all ingredients

aqua / water / eau, dipropylene glycol, alcohol denat., ascorbic acid, butylene glycol, triethyl citrate, phloretin, ferulic acid

Physician Insight

Physician image

I love patients to start the day with Phloretin CF to fight free radicals and smooth fine lines and wrinkles in the perfect concentration that our skin can use. We use an antioxidant for post-procedure homecare to complement results

Dr. Thomas Bender – Advanced Dermatology and SkinCare Centre

Learn about Dr. Thomas Bender

Complete Your Regimen


Rated 4 out of 5 by from Preventative anti aging I’m age 31 and wanted something to help prevent aging and lines and this came highly recommended. I love the feel of it but the SMELL. It smells like burnt syrup. I can tolerate it but my husband hates it. I wish it didn’t smell so awful but it’s so expensive that I plan to keep using it. Hoping the benefits outweigh the smell!
Date published: 2020-12-23
Rated 5 out of 5 by from Great for sensitive skin I have been using this product for years. It has made a tremendous difference in my skin texture and tone. I have sensitive skin that reacts to many products, but my skin just drinks this serum up. I can see the benefit when I travel and discontinue use for a bit - My skin really regresses and refreshes when I get back to my normal routines using this product..
Date published: 2020-12-02
Rated 5 out of 5 by from Great product! I’ve been using this for years. Tried a couple of the other serums and came back to Phloretin CF. I find it does a better job of removing any unwanted spots.
Date published: 2020-10-31
Rated 4 out of 5 by from Overall skin tone improvement I have been using this product for 2 months and along with triple lipid restore and have noticed an improvement in my overall skin tone and slightly diminished fine lines
Date published: 2020-10-19
Rated 2 out of 5 by from Disappointed I've been using this product faithfully every day for 3 months. I've used sunscreen every day and have super careful about wearing a hat to keep the sun off my face. I haven't noticed any difference in fine lines, and my discoloration has actually gotten worse. Won't be purchasing this again.
Date published: 2020-10-02
Rated 5 out of 5 by from Ok people, I'm a believer This actually works. Im not paid to write fact quite the opposite, I paid a truck load of money for this ha. I have Mediterranean skin and two dark spots on each of my cheeks. Trying to avoid IPL, I use an exfoliating cloth to scrub any dead skin cells and use these two products plus SPF they gave as a free gift. Yeah a difference. They are not gone but 50% lighter. Probably will be 35-40% in the end and then maybe a few IPL's. Regardless, SkinCeuticals is legit and these two products do help. I will add you need to be diligent. None of this when you remember business. No do it morning and night. Also as a tip that maybe everybody knows and I'm the last to the party, but tilt your head back and drop it directly on your face ...gently mind you. The finger transfer is a mess.
Date published: 2020-09-06
Rated 3 out of 5 by from Not effective after less than 3 months I’m extremely disappointed that I paid so much for this product. I tried to be conservative with it to make it last, but it hasn’t even been three months and the serum has turned brown and smells like rotten eggs. I was told it’s not effective once it turns brown. This is so frustrating because the product is great and really improved my skin before it went bad.
Date published: 2020-08-20
Rated 5 out of 5 by from I love all skinceuticals products. This one is def a top fav. I use this right after I tone and it has improved my skin. Im still in the middle of using it so cant tell about the full strength of it. It is very pricey though.
Date published: 2020-08-17
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