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Phloretin CF® with Ferulic Acid Vitamin C serum for face

Phloretin CF® with Ferulic Acid is rated 4.6 out of 5 by 171.
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A patented daytime vitamin c antioxidant face serum that delivers advanced environmental protection and diminishes the appearance of fine lines and discoloration. U.S. Patent No. 9,248,082.

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Product Details

Phloretin CF features a patented synergistic combination of 2% phloretin, 10% pure vitamin C (l-ascorbic acid), and 0.5% ferulic acid for enhanced protection against atmospheric skin aging – environmental damage and premature signs of aging caused by free radicals from UVA/UVB, infrared radiation (IRA), and ozone pollution (O3). In addition to antioxidant protective benefits, Phloretin CF improves the appearance of discoloration, fine lines, and uneven skin tone.

  • Provides advanced environmental protection by neutralizing damaging free radicals
  • Improves the appearance of discoloration and overall skin tone
  • Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours
  • Paraben-, fragrance-, and dye-free
  • Ideal for normal, oily, and combination skin types

How To Use

In the morning after cleansing and toning, apply 4-5 drops to a dry face, neck, and chest before other skincare products. May be used on the back of the hands. It is normal for vitamin C products to darken after opening due to air and light exposure. The formula will remain effective. Once opened, it is recommended to be used within 3 months of opening.

Complete your regimen with a SkinCeuticals sunscreen. When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide the most complete protection against visible aging caused by environmental aggressors.

  • Science & Proof

  • Science

    SkinCeuticals research shows that specific combinations of antioxidants, when effectively formulated, provide superior results to each single antioxidant formulation.

    Phloretin CF is a triple antioxidant cocktail formulation shown to provide broad-range environmental protection due to a synergistic combination of 2% phloretin, 10% pure vitamin C (L-ascorbic acid), and 0.5% ferulic acid. It is formulated under the Duke Antioxidant patent. Vitamin C is a highly-potent antioxidant that is, by its structure, difficult to effectively deliver on skin. The Duke Antioxidant patent describes the formulation parameters required for effective delivery of vitamin C to skin: 1) pure l-ascorbic acid (vitamin C); 2) an acidic pH within the 2.0-3.5 pH range and; 3) a concentration between 10%-20%. SkinCeuticals is the only brand to formulate antioxidants according to these parameters.


    SkinCeuticals defines atmospheric aging as the visible result of a range of environmental aggressors on skin, including UV, infrared radiation (IRA), and pollution. Ongoing SkinCeuticals research shows that over-exposure to these aggressors may cause visible skin aging, and topical antioxidants can help prevent the impact to skin.

    Learn more about atmospheric aging and ozone pollution

Key Ingredients

  • 2% phloretin
  • 10% L-ascorbic acid
  • 0.5% ferulic acid

Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, this antioxidant neutralizes damaging free radicals, helps improve cell turnover, and improves the appearance of discoloration

Learn more about phloretin

See all ingredients

aqua / water / eau, dipropylene glycol, alcohol denat., ascorbic acid, butylene glycol, triethyl citrate, phloretin, ferulic acid

Physician Insight

Physician image

I love patients to start the day with Phloretin CF to fight free radicals and smooth fine lines and wrinkles in the perfect concentration that our skin can use. We use an antioxidant for post-procedure homecare to complement results

Dr. Thomas Bender – Advanced Dermatology and SkinCare Centre

Learn about Dr. Thomas Bender

Complete Your Regimen


Rated 4 out of 5 by from Great antioxidant! I will say I didn’t give this 5 stars because I don’t love how watery the consistency is. I prefer the gel version, as it is easier to move across the skin without wasting too much of the product.
Date published: 2020-07-24
Rated 4 out of 5 by from This is really the only c serum that helps my annoying hyperpigmentation. One star off because it is stupidly expensive and in that ridiculous dropper bottle.
Date published: 2020-07-23
Rated 5 out of 5 by from BEST VITAMIN C THERE IS. I've used the Skinceuticals CE ferulic and it's good, but this is a much lighter formula. I have combo skin so I prefer something that doesn't feel heavy on my face. There are no cons to this product as this brand is backed by years of research. You are better off paying a premium price to get something that works vs something at the drugstore that contains a low percentage of vitamin C and nothing in the formula to stabilize it.
Date published: 2020-07-20
Rated 5 out of 5 by from my skin is glowing! I work next to a dermatologist who recommended this product for my age spots, large pores, dull skin, fine lines and wrinkles. It reveals glowing skin on the first use due to the coating and with repeated use it continues to improve skin texture. It is the first skin product that I have used that "works".
Date published: 2020-07-19
Rated 5 out of 5 by from This is one of the best vitamin C serums for people who have acne prone skin. I use either this serum or the iS CLINICAL pro-heal serum in the morning after cleansing, and before moisturizing/sunscreen.
Date published: 2020-07-15
Rated 4 out of 5 by from Best serum for skin that tends to break out. Serums with vitamin E in them do not work well with my lifelong acne issues
Date published: 2020-07-14
Rated 5 out of 5 by from WOW! I received this product 2 weeks ago, and all I can say is WOW! I can't believe the difference after my 1st use. I am a lifetime customer, and I look forward to trying more Skin Ceuticals products.
Date published: 2020-07-09
Rated 5 out of 5 by from This serum absorbs very quickly and is very light and layer-able. It smells like espresso and maple syrup, but the fragrance dissipates after a few minutes. A little bit of this product goes a long way!
Date published: 2020-06-29
Rated 5 out of 5 by from I love this vitamin C serum. It improves the texture and look of my skin. It makes my acne-prone skin appear healthier without breaking me out. It’s expensive but I’ve been able to use a drop a day to every other day and made the bottle last a year and a half. When I ran out, I tried to substitute it with another vitamin C serum (due to price) but it just wasn’t the same and ended up buying another bottle. Keep the bottle in a cool dark spot or else it will oxidize and turn brown.
Date published: 2020-06-28
Rated 4 out of 5 by from This product has not only helped clear up the acne I have struggled with for a long time but has also cleared up harsh redness that my skin is always suffering from. I would definitely tell anyone to buy this!
Date published: 2020-06-23
Rated 5 out of 5 by from Game Changer! I have sentive and oily skin, so I was hesitant to try something new, especially considering the price but my dermatologist recomended this and I love it! It has smoothed my skin and given me a healthy glow. Even after one bottle, I have seen a noticable difference in the appearance of my skin. Definitly worth the cost!
Date published: 2020-05-26
Rated 1 out of 5 by from Sample size review I have used a variety of dermatological products, inclduing a variety of SkinCeutical products. I was provided a sample size of this and it smells like hot-dog water. I can't imagine using this consistently based on the smell.
Date published: 2020-05-25
Rated 5 out of 5 by from This is my first step before applying all of my other products each morning, and I definitely recommend it. I struggle with pigment issues and this helps even and brighten my skin.
Date published: 2020-05-24
Rated 5 out of 5 by from This product is pricy, but I hate to say it is worth it! I use this one rather than the CE Ferulic because this is better suited for troubled skin/acne and is less oily. I feel as though it helped lighten up some of my acne scars. I really like the consistency of the product as well - light and absorbent. Can’t wait to try more skinceuticals products!
Date published: 2020-05-20
Rated 5 out of 5 by from Love, love, love this product! I started using it about 3 weeks ago after my skin started getting dry and dull. It has greatly improved the texture and tone of my skin and now it’s glowing. Absolutely recommend to anyone wanting to get rid of dull looking skin!
Date published: 2020-05-19
Rated 5 out of 5 by from I started with a sample of C E Ferulic and Phloretin CF and I much prefer Phloretin CF for my combination/ acne skin. Phloretin CF brightened my skin without making it oily. It’s gradually helping with discolouration from acne scars but it’s not a miracle worker - patience is key! I would definitely recommend and repurchase.
Date published: 2020-05-01
Rated 5 out of 5 by from Love This Product! First I want to thank SkinCeuticals for sending me a complimentary sample of CE Ferulic without having to purchase anything. CE Ferulic and Phloretin CF are two of the best products I have ever used. Typically I use Phloretin CF. Living part time in Arizona and enjoying the sun can be hard on your skin. Phloretin CF combined with Physical Fusion UV Defense sunscreen with SPF 30 protect my skin all day. It amazes me how well those 2 products work together to prevent sun damage. I'm 59 and have had oily skin all my life with acne issues. Skinceuticals products are by far the best I've used. Its pricey but well worth the results. I wish I would have discovered these products when I was younger. I use other SkinCeutical products too, but the Phloretin CF and CE Ferulic are the best for me. Thanks again for the complimentary sample!
Date published: 2020-04-28
Rated 5 out of 5 by from Excellent Addition to My Skincare Routine I started using this product 3 months ago, and I am impressed. The overall radiance of my skin is improved. Of course, I can’t see the preventative effects of this Vitamin C yet, but after reviewing the scientific data on Vitamin C (and this Vitamin C in particular!) I am confident I’m purchasing a great product that prevents future damage.
Date published: 2020-04-25
Rated 5 out of 5 by from I love love this! I break out easily and so used this on half my face to see if I could find a reaction. What I found after a week was that the side I used this on was dramatically different than the side I did not use this on! My pigmentation was reduced, fine lines smoothed and my skin glowed on the side I applied this. It also did not break me out. I love this!
Date published: 2020-04-25
Rated 4 out of 5 by from Was given a sample of this from my dermatologist and was shocked how well it works. Left skin smooth, shrunk pores and faded some sun spots. Unfortunately I can’t afford the price and would look for a dupe out there.
Date published: 2020-04-24
Rated 5 out of 5 by from One of the only serums you will ever need. There is a reason why doctors always recommend this product. It works. Don’t waste your money on serums from Sephora. Go with the medical grade product
Date published: 2020-04-20
Rated 5 out of 5 by from Must Have for Oily/Combo Skin!! I had previously used CF Ferulic & while I had great results it was a bit too heavy for my oily skin. So I gave this a try as its for oilier skin types and it’s amazing!! It’s perfect for my skin & I saw results immediately. It brightens & evens my skin like no other. A little goes a long way so that helps justify the price as well as the results. Skinceuticals makes great products, Ive yet to find any other brand that gives me these kind of results.
Date published: 2020-04-17
Rated 5 out of 5 by from Great for combination skin ! I was a CE Ferulic user. Due to my young and acne prone skin my dermatologist recommend switching to Phloretin CF. I love it!!!! It helped with my breakouts and balancing the PH of my skin. I also had post acne pigmentation that has been improving alot! If you suffer from adult acne and pigmentation this is a great product.
Date published: 2020-04-05
Rated 5 out of 5 by from This product is a great exfoliating treatment! It came very good packaging and is great size. This product could prove by making the nozzle more accurate. It is extremely effective. I would recommend to people who have acne, oily, or mixture skin!
Date published: 2020-04-04
Rated 5 out of 5 by from EVERYONE NEEDS AN ANTIOXIDANT IN THEIR SKINCARE ROUTINE!!! This is amazing for people with more oily, acne prone skin! It does wonders to help with antiaging, protecting your skin from pollution, and further sun damage. This antioxidant combination helps with brown spots as well! Combine this with a sunscreen and that alone is a great skincare routine!
Date published: 2020-03-16
Rated 2 out of 5 by from Did not work for me, did not get rid of my ance scars. And did not prevent newer pimples that I get from stress. I have oily sensitive skin. Also it's super expensive but not really worth it. The formula is not clean either. It made the skin slightly greasy too.
Date published: 2020-03-12
Rated 5 out of 5 by from Love this vitamin c product! I have been trying a sample of this product and have already noticed a difference after a week. It instantly absorbed into my skin and faded acne scars/ brightened my skin. I think this product is worth the splurge!
Date published: 2020-03-10
Rated 5 out of 5 by from Will never be without Just started using skinceuticals and this particular product is amazing. My skin is glowing...have actually had comments (which I never do.) Smells like espresso, but I guess that's ok since I love coffee!
Date published: 2020-02-11
Rated 5 out of 5 by from I use this everyday in the morning and constantly repurchase. I know it is expensive but it is completely worth the price and it lasts a few months, even though I do wish it came in a bigger bottle.
Date published: 2020-02-06
Rated 3 out of 5 by from I’ve used this every morning for nearly 7 months now, and the bottle still isn’t empty! The price point is insane, but I’m always willing to splurge on medical-grade skincare products. I will say, I’ve noticed my acne scars have faded over time and any active acne I have doesn’t seem to leave any red or dark marks on my face, even if I touch/pick at them (although I shouldn’t be). The smell is not great, but I’ve grown accustom to it. Overall, I feel the product has helped with my general complexion issues, but it’s nothing outstanding for the $120+ price point. When my bottle runs out I plan to stop using it/replace with a cheaper alternative and see if I notice a difference or miss the product. I feel like I won’t necessarily, but only time will tell.
Date published: 2020-01-31
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  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.12
  • cp_2, bvpage2n
  • co_hasreviews, tv_2, tr_169
  • loc_en_US, sid_635494328004, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_skinceuticals-us
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