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Phloretin CF® with Ferulic Acid Vitamin C serum for face

Phloretin CF® with Ferulic Acid is rated 4.6 out of 5 by 172.
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A patented daytime vitamin c antioxidant face serum that delivers advanced environmental protection and diminishes the appearance of fine lines and discoloration. U.S. Patent No. 9,248,082.

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Product Details

Phloretin CF features a patented synergistic combination of 2% phloretin, 10% pure vitamin C (l-ascorbic acid), and 0.5% ferulic acid for enhanced protection against atmospheric skin aging – environmental damage and premature signs of aging caused by free radicals from UVA/UVB, infrared radiation (IRA), and ozone pollution (O3). In addition to antioxidant protective benefits, Phloretin CF improves the appearance of discoloration, fine lines, and uneven skin tone.

  • Provides advanced environmental protection by neutralizing damaging free radicals
  • Improves the appearance of discoloration and overall skin tone
  • Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours
  • Paraben-, fragrance-, and dye-free
  • Ideal for normal, oily, and combination skin types

How To Use

In the morning after cleansing and toning, apply 4-5 drops to a dry face, neck, and chest before other skincare products. May be used on the back of the hands. It is normal for vitamin C products to darken after opening due to air and light exposure. The formula will remain effective. Once opened, it is recommended to be used within 3 months of opening.

Complete your regimen with a SkinCeuticals sunscreen. When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide the most complete protection against visible aging caused by environmental aggressors.

  • Science & Proof

  • Science

    SkinCeuticals research shows that specific combinations of antioxidants, when effectively formulated, provide superior results to each single antioxidant formulation.

    Phloretin CF is a triple antioxidant cocktail formulation shown to provide broad-range environmental protection due to a synergistic combination of 2% phloretin, 10% pure vitamin C (L-ascorbic acid), and 0.5% ferulic acid. It is formulated under the Duke Antioxidant patent. Vitamin C is a highly-potent antioxidant that is, by its structure, difficult to effectively deliver on skin. The Duke Antioxidant patent describes the formulation parameters required for effective delivery of vitamin C to skin: 1) pure l-ascorbic acid (vitamin C); 2) an acidic pH within the 2.0-3.5 pH range and; 3) a concentration between 10%-20%. SkinCeuticals is the only brand to formulate antioxidants according to these parameters.


    SkinCeuticals defines atmospheric aging as the visible result of a range of environmental aggressors on skin, including UV, infrared radiation (IRA), and pollution. Ongoing SkinCeuticals research shows that over-exposure to these aggressors may cause visible skin aging, and topical antioxidants can help prevent the impact to skin.

    Learn more about atmospheric aging and ozone pollution

Key Ingredients

  • 2% phloretin
  • 10% L-ascorbic acid
  • 0.5% ferulic acid

Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, this antioxidant neutralizes damaging free radicals, helps improve cell turnover, and improves the appearance of discoloration

Learn more about phloretin

See all ingredients

aqua / water / eau, dipropylene glycol, alcohol denat., ascorbic acid, butylene glycol, triethyl citrate, phloretin, ferulic acid

Physician Insight

Physician image

I love patients to start the day with Phloretin CF to fight free radicals and smooth fine lines and wrinkles in the perfect concentration that our skin can use. We use an antioxidant for post-procedure homecare to complement results

Dr. Thomas Bender – Advanced Dermatology and SkinCare Centre

Learn about Dr. Thomas Bender

Complete Your Regimen


Rated 3 out of 5 by from I’ve used this every morning for nearly 7 months now, and the bottle still isn’t empty! The price point is insane, but I’m always willing to splurge on medical-grade skincare products. I will say, I’ve noticed my acne scars have faded over time and any active acne I have doesn’t seem to leave any red or dark marks on my face, even if I touch/pick at them (although I shouldn’t be). The smell is not great, but I’ve grown accustom to it. Overall, I feel the product has helped with my general complexion issues, but it’s nothing outstanding for the $120+ price point. When my bottle runs out I plan to stop using it/replace with a cheaper alternative and see if I notice a difference or miss the product. I feel like I won’t necessarily, but only time will tell.
Date published: 2020-01-31
Rated 5 out of 5 by from My favorite Vitamin C serum! I have oily summer/dehydrated winter skin with a lot of sun spots and this is wonderful! Great daily protection and has really helped to keep my spots at bay. One negative thing is price, but I haven’t found anything else like it. Dropper packing isn’t bad, but wish it came with an airtight pump.
Date published: 2020-01-29
Rated 5 out of 5 by from Magic!!! This stuff is amazing!! Two days with the system and my pores are tighter, my skin is smoother. Omg I use a lot which you don’t have to but this is the magic stuff. I am also black so most times I wonder if this will work. It did!
Date published: 2020-01-28
Rated 5 out of 5 by from If you have problematic skin that is prone to rosacea, acne, etc then this is the Vitamin C serum you should be using. Skinceuticals was developed and tested by a Duke dermatologist and is a medical grade product. With consistent use your skin will brighten and your skin tone evens out. I consider this a holy grail product and will use it until something better comes along, although I’m not sure if that could ever happen. It’s pricey but you only need a couple of drops each day so it lasts a long time! Worth every single penny.
Date published: 2020-01-26
Rated 5 out of 5 by from Makes a difference I’ve gone through 2 bottles and will continue to purchase forever. I have very oily skin and this is perfect. It seems to make my skin look more even than any other product. It is helping my neck also.
Date published: 2020-01-21
Rated 5 out of 5 by from If I had to pick one product to have in my skincare drawer, this would be it! The Skinceuticals Phloretin Treatment is pricy but worth every single penny. It changed my skin - decreased the size of my pores, diminished my sun/dark spots, improved my skin texture to name just a few benefits. Plus, as a New Yorker having a product that protects my skin and serves as an antioxidant against all of the particles that are in the air is so necessary! Love this product!
Date published: 2020-01-14
Rated 5 out of 5 by from An all time favorite!!! This serum will give you the glow everyone talks about. The phloretin helps to combat pigmentation together with the vitamin c. Its not as harsh on the skin, but it will take sometime for the skin to get use to it. Might feel a slight tingle the first few uses. Its ideal for oily combo skin, however its quite pricey, but it does go a long way. Its the only vit c serum thats water based meaning its pure absorbic acid and more importantly its stabilized.
Date published: 2020-01-09
Rated 4 out of 5 by from This product is pretty lightweight. I have been using it every day for the past six months and I have no complaints. I started using it as a part of my anti-aging regimen so it’s hard to say if it’s really working but it does feel nice on my skin. The price point is a bit high but I’m a huge SkinCeuticals fan so I will continue using.
Date published: 2019-12-29
Rated 4 out of 5 by from Goes on a little heavy, like the bestselling CE Ferulic. Was supposed to be better for oily skin, but I didn’t notice much of a difference. As long as you make time for it to sink in and do its thing, it’s great. My skin is brighter and more even after a couple of months. (Melasma and the occasional breakout are my biggest skin woes.) Diligent SPF is key though!
Date published: 2019-11-30
Rated 5 out of 5 by from This is my second bottle, and I will probably be repurchasing all my life. Ive tried other vitamins C’s and there nothing like this one. My skin has gotten brighter, most of my hyperpigmentation is completely gone, and some how it has helped me with my breakouts. I use this serum daily before moisturizer. It is an expensive serum, it is around $166 dlls, but its worth it. Love it!! Best skincare serum ever!
Date published: 2019-11-27
Rated 5 out of 5 by from Polar opposite of C E Ferulic. Has not broken me out so far, doesn’t seem to dry me out, and doesn’t smell nearly as awful!
Date published: 2019-10-28
Rated 5 out of 5 by from I have been using this product for about 1 month, and I’m really liking it . I know that it’s kind expensive, but I believe I’ll be able to use it for almost 5 months.. only 5 drops and you are ready to go. [product:skinceuticals-phloretin-cf-broad-range-antioxidant-treatment]
Date published: 2019-10-26
Rated 4 out of 5 by from Great for anti aging so i use it daily cuz we all need an antioxidant! But it hasn’t made a huge difference in my skin. It doesn’t feel a bit healthy but it’s not like a holy grail. I just wanna age well :)
Date published: 2019-10-24
Rated 2 out of 5 by from Immediately oxidized I was unaware that C products need to be kept in dark, dry areas. So when I first opened the product and found it was yellowish-brown I assumed that was just the regualr color. Eventaully I read online that this serum should be clear. I reached out to skinceuticals but didn't recieve a reply.
Date published: 2019-10-23
Rated 4 out of 5 by from I finally took the plunge with my wallet, and bought this product. I started using it on October 1st. I'm 48, I have combination and sensitive skin. 6 months ago after my 1st visit to Hammam spa in Toronto, I booked a facial that made me reconsider my entire face routine. Anna introduced me to products I now use daily and these have made a huge difference overall. However I felt I needed something that would compliment and further my desire for results I was looming for. I wanted a product that would even out my skin, and firm it, and protect it against environmental pollutants. This amazing product is getting me what I was needing and looking for. I started showing a faint line in the lower left area of my lip. I've Ben using this magic elixir for only 9 days....The line is gone. I was actually looking for it tonight...I even had my husband look as well. He couldn't find it. I can't wait to see what this product will do in another 3 weeks. So far, I'm a believer.
Date published: 2019-10-10
Rated 5 out of 5 by from Glowy perfection in a bottle. I have been using the Phloretin CF since I got a chemical peel in March. I love this product. My acne scars are completely gone and my face is smooth and it glows. Additionally, I invested in a small cosmetic refrigerator; therefore, I have not notice any smell about this product. The product smells like how it smelt when my Dermatologist put it on after my peel. Invest in this product and you will not go wrong!
Date published: 2019-10-07
Rated 3 out of 5 by from Again Skinceuticals really was a bummer for me! So many great reviews, I tried a bunch of their serums and products but all without any skin impact. I also dislike that this vitamin C was a little oily, not the ideal refreshing texture I would like in a serum.
Date published: 2019-10-06
Rated 5 out of 5 by from Again crazy expensive but it does work beautifully. It has a light coffeeish smell to it but not overbearing. It definitely makes your skin feel and look more firm and youthful and diminishes the appearance of fine lines
Date published: 2019-10-03
Rated 4 out of 5 by from I love everything about every single Skinceuticals product. I have been using these products for years.
Date published: 2019-09-26
Rated 5 out of 5 by from Amazing. Makes my skin so shiny and smooth. Reduces my wrinkles and tightens my skin. Perfect for under sunscreen in the morning
Date published: 2019-09-07
Rated 4 out of 5 by from Hopeful but inquiring about the smell I’ve gotten a sample of this from my facialist and I want to continue using it, but I know that vitamin c is extremely unstable so I’d like to know if my product is spoiled before I continue using it. It smells like smoked meat. Literally. And it’s yellowish in color. I know that when vitamin c serums turn color, that means they are turning bad and therefore losing efficacy. Can you tell me how it’s supposed to smell when it’s fresh? Does it always have a smokey scent to it? Lol
Date published: 2019-09-06
Rated 5 out of 5 by from nice Love the product, smell is not so great but results are worth it. Product is a little pricey.
Date published: 2019-08-12
Rated 5 out of 5 by from I am all about antioxidants and preventative aging. I think this product is a great alternative for those who do not like their Vitamin C serum. It feels lightweight on the skin and gives my skin a healthy glow. Since this is more about preventative skincare, i can not attest to any extreme benefits
Date published: 2019-07-31
Rated 5 out of 5 by from My aesthetician recommended I use this to unclog my congested skin. I have oily combo skin and before I used Phloretin CF I had a lot of little black heads in my T zone. While I wouldn't say this is a cure all, I will say I've noticed a difference in my skin texture - fewer small bumps, and I feel my skin has more of a glow than it did previously. I love Skinceuticals brand and I think, while pricey, the products they put out are worth it.
Date published: 2019-07-31
Rated 5 out of 5 by from Have you been waiting for a product that will change your skin life forever, because look no further. My whole routine is skinceuticles but this little beauty works overtime and really does it all! I will buy this for the rest of my life, and I can’t stress how potent and effective the ingredients are.&nbsp;<br><br>If you were only to pick one serum, this would need it be it!&nbsp;
Date published: 2019-07-27
Rated 5 out of 5 by from Skin looks amazing I was given this after IPL treatments. I love this stuff, my skin looks great. I've tried buying similar products off amazon, and they do not compare to this.
Date published: 2019-06-19
Rated 5 out of 5 by from What did I do before this?!? After doing a lot of research, I decided to give this a try. Wow. I was really impressed. I have been using it for about a year now with great results. It is my very favorite Skinceuticals product. Highly recommend!
Date published: 2019-06-09
Rated 5 out of 5 by from My favorite! I use this with a couple other products that skinceuticals offer and seen such a difference in my skin. A bit pricey but lasts a while and to me so worth it.
Date published: 2019-06-09
Rated 5 out of 5 by from Must have!! This stuff is amazing!! I quit using it after about five years and tried other things only to come back...this stuff helps to reverse aging!! Must have product!!
Date published: 2019-06-08
Rated 4 out of 5 by from great product I received a sample and I noticed a difference in my skin in a week. My skin became radiant and growing. I bought a full size and I absolutely love it.
Date published: 2019-06-08
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  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.12
  • cp_3, bvpage2n
  • co_hasreviews, tv_2, tr_170
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