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Retinol 0.5 Retinol night cream for face

Retinol 0.5 is rated 4.3 out of 5 by 47.
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A concentrated night cream with pure retinol improves the appearance of visible signs of aging and pores while minimizing breakouts

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Product Details

Retinol 0.5 contains 0.5% pure retinol and is enhanced with the latest stabilization and delivery technologies to ensure a steady, even release. Designed to help diminish the appearance of fine lines, wrinkles, and skin discoloration, this retinol night cream can refine the appearance of pores, while reducing the appearance of blemishes associated with problematic skin.

  • Promotes cell turnover
  • Improves the appearance of fine lines, wrinkles, discoloration, pores, and blemishes
  • Formulated to minimize irritation commonly associated with the use of retinol night creams
  • Specialized packaging preserves retinol potency
  • Non-comedogenic, paraben-, fragrance-, and gluten-free
  • Ideal for skin preconditioned with Retinol 0.3

How To Use

In the evening, apply 4‐5 drops to clean dry skin, avoiding the eye area. Allow product to absorb before applying other skincare products. Limit initial use to once or twice a week, gradually increasing frequency to every other night, then every night as tolerated. It is important to establish consistent skin tolerance before advancing to a higher concentration.

Retinol may increase photosensitivity. Always use a high-protection, broad spectrum sunscreen when using this product.

As a precaution, retinol cream products should not be used by pregnant women or women who intend to become pregnant in the near future. Though there are no reports of topical retinol having any negative effect on fetal development, always consult a physician.

  • Science & Proof

  • Science

    Topical retinols have extensively been used by dermatologists to help combat and reverse the visual effects of aging, such as wrinkles, laxity, and discoloration. Retinols because they accelerate cell turnover, can also improve blemishes and the appearance of pores. The retinol molecule is highly-sensitive and vulnerable to breakdown if not properly protected. Retinol 0.5 employs an optimized delivery system and protective packaging to ensure stability and efficacy of pure retinol. This retinol night cream works with skin’s natural lipid structure to promote optimal absorption.

Key Ingredients

  • 0.5% Retinol
  • Soothing complex

A derivative of vitamin A, this powerful molecule promotes cellular turnover to help improve the appearance of fine lines, wrinkles, and discoloration. It also helps minimize blemishes while reducing the appearance of pores.

Learn more about Retinol

See all ingredients

aqua / water / eau, propanediol, dimethicone, cetearyl ethylhexanoate, alcohol denat., dipropylene glycol, ammonium polyacryloyldimethyl taurate, allyl methacrylates crosspolymer, acrylamide/sodium acryloyldimethyltaurate copolymer, hydrogenated lecithin, isohexadecane, retinol, phenoxyethanol, caprylyl glycol, polysorbate 20, isopropyl myristate, sodium citrate, boswellia serrata gum, polysorbate 80, dimethiconol, trisodium ethylenediamine disuccinate, bisabolol, bht, sorbitan oleate, citric acid, propyl gallate

Physician Insight

Physician image

I always start my patients on Retinol 0.5 at night. It is a great way to achieve a visible change in skin tone, and an essential building block for a solid skin care program.

Dr. Richard Zeff – Zeff & Wilson Plastic Surgery

Learn about Dr. Richard Zeff

Complete Your Regimen


Rated 5 out of 5 by from Great Results! I have been using this Retinol 0.5 about once to twice a week and i have been using this for about a year now. I love how this product works. My skin Glows so much! I'm so glad i found this product
Date published: 2019-01-25
Rated 4 out of 5 by from Been using for 2 months 25 years old, went in guns blazing with this, using every night as a part of my nightly regimen. It makes my skin feel so good and smooth immediately after using it. I've noticed a little improvement in forehead lines but its only been two months so we'll see. I thought it would help my large pores/blackheads on my nose but it really hasn't at all. I know it takes time so I'll stick with it and maybe bump to the 1.0 after this one finishes. Did not have any redness/peeling/drying like other reviewers at all.
Date published: 2019-01-06
Rated 1 out of 5 by from I didn’t see results so far I bought this product when my skin and acne was really better (I used 2 bottles of Blemish + Age defense serum and LHA cleanser and toner), because they were good to acne and skin tone but not to blackheads. I thought Retinol would help me with this problem and I read about 3 months to effect.. but it was aggressive product to my skin, and acne came back strong probably because I stopped other products (as recommended). I just used twice a week, sometimes once a week but it was bad as well. Now I will keep using on forehand, to see because this is the only part of my face that didn’t have problems.
Date published: 2018-11-17
Rated 5 out of 5 by from Lightens dark spots from melasma I bought this about two months ago. It is very strong and i use only once or twice a week. It does make my skin peel as it should. It is slowly taking away the brown from my melasma. I recommend this highly. I am anxious to try the rest of their products.
Date published: 2018-11-16
Rated 4 out of 5 by from Great product I have been applying it every other night since July. I see the difference on my skin.
Date published: 2018-10-08
Rated 5 out of 5 by from Best Treatment I've Found I have been suffering from acne since I was 13 (now 26). After a respite in my early 20s I had resurgence after changing birth control. I tried everything in the drug store and natural remedies; they would work for a few weeks and then ultimately stop working. My mom suggested the Retinol 0.5 cream to me after she noticed it helped with her blemishes (she used it for anti-aging). While this is more than I was comfortable spending I was desperate. After a week I saw a dramatic difference in my skin, after 2 weeks all of my pimples were completely gone (there are still sometimes new ones, but they're small and go away after a day or two). After 3-4 weeks of using this product, not only did my skin become more clear than I have ever seen it get in my life, but my old acne scars - ones which I had had for YEARS - were going away. I have been using this product now for about 7 months and I cannot recommend it highly enough. I have even gotten a few of my friends turned onto it for their skin ailments and they have all also seen incredibly positive results. My only complaint is that I wish there was more of it in each tube! But I am still giving it 5 stars.
Date published: 2018-10-08
Rated 5 out of 5 by from Works Great! I just started with Retinol 0.5% 2 months ago. My skin looks firmer and clearer. I read that Retinols take time to work. I believe it will show better results as I adjust with how often I apply it. I started using it 3x a week and now I use it every other night. I use H.A Intensifier after to help with the flakiness and dryness at night. I use C E Ferulic acid and the tinted SPF 50 of Skinceuticals in the morning. I have not used foundation for 2 months now since I started with my Skinceuticals routine. I use mascara, eyeliner, bronzer, lipstick with only spf under and I look great and glowing. I will be getting the triple lipid restore when I start using this retinol 0.5 every night in conjunction with all my Skinceuticals products. So far, I’m very happy with the results. I will be getting the 1% once I’m done with my .5%.
Date published: 2018-08-10
Rated 5 out of 5 by from 29/m I love it, I've been using it for 8 months to help large pores in my t-zone. I started by using it twice per week, then every other night, and now almost every night. If you notice redness or flaking, slow down and use it less. You'll get there, it just takes time. After six months, my pores looked less deep, so I just bought my second tube of 0.5.. and in another 8 months maybe I'll be able to bump up to the 1.0.
Date published: 2018-06-04
Rated 4 out of 5 by from Wonderful This stuff is amazing! Saw results within two weeks. It does dry your skin quite a bit so you just have to make sure you always use a moisturizer 30 minutes after applying the retinol.
Date published: 2018-02-17
Rated 5 out of 5 by from Great Results I never leave reviews for products, but I was thinking this morning that I really must come review this retinol cream. I have been using it every other night for 6 months and all of a sudden I am seeing excellent results! My skin started gradually changing and now I can really tell the difference. My skin is smooth, fine lines around my eyes has basically disappeared. The redness around my nose has lightened tremendously. In the past month, 3 different people have told me how great my skin is looking (one of them is a skincare professional). Also, my previously oily skin has mellowed out and I no longer have to use blotting strips throughout the day. It is a slow process but I am very happy with the results.
Date published: 2018-01-30
Rated 2 out of 5 by from Made my skin look shiny I didn't realize that one of the side effects of over exfoliation was having super shiny skin! I was thinking that I could continue to use this product every other day since I didn't have any redness or any other irritation. I realize now that this product should not be used that frequently. I stopped using it for now hoping my skin will go back to normal. If I do use it again it will be once a week if that.
Date published: 2018-01-27
Rated 5 out of 5 by from Renewed my skin...and self-confidence I am almost 36 and have been dealing with 'adult acne' for the past couple of years. This cystic acne showed up every couple of days, lasting for days. I eat clean, workout regularly and have never had a problem with acne before the age of 34. So, I tried everything...changing makeup, skin care regimes, elimination diets. There were mornings I cried because I was embarrassed to leave the house and be seen with these massive bumps on my face. Finally, I decided to splurge and try SkinCeuticals after a friend had recommended it. I am about three weeks in now and I have not had any cystic acne since the day I started using the product. I am in love. I use the face wash, lotion, retinol and sunscreen. My face is back to my normal and I'm over the moon. Spend the's worth every penny!
Date published: 2017-06-01
Rated 5 out of 5 by from Love, love! This is the one skincare product that I cannot do without. I have sensitive, thin skin and this formulation works great. I have a tube that bought from estheticion a year ago. Still have product in tube. It lasts a long time for me. I am so disappointed to hear about the problems with the pump system. Please return to the tube! Thank you.
Date published: 2016-09-16
Rated 5 out of 5 by from Love this product First off, I see nothing wrong the tube this product comes in, its not a pump, its a tube. Been using this for almost 3 weeks, pores are getting smaller, skin is starting to peel...but that's what I want it to do. Love the 0.5 and looking forward to using the 1.0 strength. I haven't used any other SC products but I can assure you this stuff is worth every penny. I NEVER write reviews, just love this product so much I had to share.
Date published: 2016-04-27
Rated 4 out of 5 by from Great product. Hate the tube. This is such an amazing product. I have truly seen a difference in my skin by using this about twice a week along with my Phloretin CF serum and LHA Cleanser. My skin has done a complete 180 with Skin Ceuticals. I was suffering from bad breakouts (I have very oily T-zone). However, I wish the tube for this was a little bit more user friendly. I have noticed the hard/metallic like tubing is really hard to squeeze and when I get to the bottom of my tube it's even harder to get the last bit of my product out. Being that this isn't the most inexpensive product, an improvement in the tube would have gotten this product 5 stars.
Date published: 2016-03-31
Rated 5 out of 5 by from Can't say enough good things I highly recommend this product to anyone struggling with acne, uneven texture, or large pores. Since I became pregnant again my skin broke out with severe acne. After giving birth the problem remained. My esthetician recommended I use s.c. regiment. This + my cleanser, toner has been a life saver. As you have read, ease into this productand use proper spf. I also recommend peels from sc provider. Pores are so much smaller and my break outs have been under control. Learning to love my skin! God bless!
Date published: 2015-07-26
Rated 5 out of 5 by from Makes my skin smooth! I have been using this product for about 2 mos now. I just began using it nightly. I haven't experienced any redness. My skin feels so smooth and is looking brighter! I love the SkinCeuticals line!
Date published: 2013-07-31
Rated 5 out of 5 by from Super Retinol!!! I have oily, but very senitive skin. I bought this Retinol for correcting fine lines. I have been using it for two weeks and my face looks radiant. I have had some light flaking, that's to be expected. I have only been using it at night aswell as I am trying to acclimate my skin to it. I highly recommend this Retinol to all the ladies who want to keep their faces smooth and keep those pesky lines away!!!
Date published: 2013-07-25
Rated 5 out of 5 by from Amazing! I've been using Retinol 0.5 for two weeks and have noticed such a difference! My pores are smaller, skin is clearer and smoother. Best of all, I can see my age spots, from a lifetime in the sun, disappear! Even some freckles that I thought would be there forever are going away! Love this product!!! If the results are this good so early on, I can't wait until I graduate onto Retinol 1.0!
Date published: 2013-04-02
Rated 5 out of 5 by from Hoping the packaging change solves pump issues I have been using this product for about 6 months now, and absolutely love it! The first pump I received didn't work at all, even when following the instructions, but the replacement worked fine. After using this product for a few weeks, I noticed that my skin is much clearer. I was always frustrated that even at 28 I was getting acne, and after switching to this product I rarely get breakouts. I have noticed a very slight change in my fine lines, although I am upgrading to the 1.0 the next time I order since I never had any sensitivity issues with this product and I want to see if that makes a bigger difference. However, I make sure to use sunscreen every day when using this product, even on cloudy days in the middle of winter.
Date published: 2012-11-09
Rated 5 out of 5 by from Results! My skin is noticeably smoother! It helped with blemish and blotchiness. I have tried every brand and I love skinceuticals.
Date published: 2012-04-20
Rated 5 out of 5 by from Great Product! Within days my little acne on my chin cleared up. I use this in the a.m. and p.m. and I tolerate it well. No irritation and no dryness. May go to the 1.0 when I've used this .5 up. I do hope to see improvement on fine lines as I continue to use but have not noticed any improvement as of yet, but it's been only a couple weeks. The pump worked PERFECTLY for me every time. I would suggest to other to read the instructions....pump slowly :)
Date published: 2012-03-20
Rated 4 out of 5 by from Retinol 0.5 I purchased this product from a spa and had to have it replace due to the pump not working, but the 2nd pump quit working also....when I cut it open, it was still 1/2 full. Customer service was GREAT and replaced the bottle after I gave information on where I purchased it. Thanks!
Date published: 2012-03-19
Rated 4 out of 5 by from Love it. I was scared I would have problems with the pump, but it worked perfectly. My skin looks great. I actually can't wait to get the 1% retinol, because my skin isnt super sensitive. I just turned 28, and I have little baby wrinkles beginning to form in the corner of my eyes and above my eyebrows. After I use this, my skin feels soft and just glows from the inside. I use it 3 or 4 days a week.
Date published: 2012-03-08
Rated 5 out of 5 by from Excellent product, awful packaging I read all the reviews of this product including the problems with the packaging and decided to try it anyway. I loved the product. Unfortunately I got to use the product for only 2 weeks before the pump failed. A very expensive product for two weeks' use. I should have listened to my gut instinct that said DO NOT BUY THIS PRODUCT. This company won't make this situation right. They've lost me as a customer.
Date published: 2012-02-29
Rated 4 out of 5 by from Once a skeptic, but I am inpressed I purchased this product because it was highly recommended by my facialist. I have used retinol/vitamin A derived products in the past, and found the only thing they did was give me a bad looking sunburn and peeling skin. Well, this product did the same, however the 'after' results were pleasing enough to continue. I am 29 and starting to notice small lines around my brow, the 'I am concentrating' ones. I was considering botox, because I thought that would be the most efficient way to eradicate them. I am glad I did not go to that drastic measure, especially while still young. I will continue using this product on my forehead for fine lines, and chin for my hormonal acne. I found it to be too sensitive for my under eye area, and using it on my nose just gives me a red nose and I am concerned about using a retinol product on a sun sensitive area such as the nose, even when using sunscreen during the day. No bottle/pump problems here. I bought it at a spa, not through the mail, so maybe it's a handling/shipping issue why people are having issues. The product itself is definitely correcting. I only need to use twice a week, which I have read is the right amount of time to use this type of product.
Date published: 2012-01-12
Rated 1 out of 5 by from horrible packaging I was so excited to receive this product in the mail yesterday but the pump does not work!! It's brand new!! I can't review the product because I can't get it out of the bottle...after reading the reviews I realized I'm not the only one who's having issues with the pump. They need to redesign the bottle. I like this line, and I'm sure this stuff works, but I need them to help me getting it out of the bottle first!
Date published: 2012-01-05
Rated 1 out of 5 by from Effective... if you can get it dispensed! I love what this product did to my skin in just four applications; hate that I can't test its effectiveness any longer since the pump stopped working on day 4 of use. Actually, the first one I bought never worked (no matter how I cajoled the container) and I had to replace it. The second one lasted about a week. What a shame! I understand, from reading these reviews, that I'm by no means an isolated case, but if Skinceuticals knows about the issue (and you'd have to live on a different planet not to) - why aren't you addressing it on the Web site and in the packaging production process?? I'm dissapointed, but hope you'll fix the problem because I really like the line.
Date published: 2011-12-18
Rated 4 out of 5 by from Love it! I suffer from mild to severe breakouts, and from the three weeks i have used this products i have noticed my pores already begin to decrease in size and some have even become almost non existent. I have not had the side effects of dull, dry, peeling skin. If you are curious about a retinol product, this one is the one to buy.
Date published: 2011-10-21
Rated 4 out of 5 by from So far, so good This product is doing well so far. Been using for 3 weeks and can see lines / pores diminshing and my skin tone becoming smooth and even. No dryness issues, no peeling, no stinging. Because I seem to 'tolerate' this level of Retinol, I may bump up to 1.0%. I agree, the pump is terrible. The product needs to be in a tube or medicine dropper type of bottle.
Date published: 2011-10-06
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