Shield
Against Atmo3spheric Aging

THE SKIN’S GREATEST ENEMY IS NO LONGER JUST THE SUN

Ground level ozone (O3) pollution is shown to cause signs of premature aging.

FACING THE FACTS ABOUT OZONE POLLUTION DAMAGE

Like the air we breathe, ozone pollution surrounds us around the clock. Ozone pollution oxidizes lipids and depletes skin’s natural antioxidant reservoir, triggering a progressive cascade of damage, contributing to visible signs of aging. Ozone pollution may contribute to premature aging that can lead to the appearance of fine lines, wrinkles, and sagging skin.1

*Valacchi, G. (2010). Effect of ozone on cutaneous tissue. In Farage, M.A., Miller, K,W., Maibach, H.I. (Eds.). Textbook of Aging Skin. (411-420). Berlin: Springer. Cotovio, J., et al. (2001). Generation of oxidative stress in human cutaneous models following in vitro ozone exposure. Toxicology in Vitro. 15, 357–362. Costa, C. et al., (2010). Exposure of human skin to benzo[a]pyrene: Role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation. Toxicology. 271, 83-86.

GROUND-BREAKING SKINCEUTICALS SCIENCE

SkinCeuticals partnered with a leading ozone expert Dr. Guiseppe Valacchi to study ozone pollution in live skin. This research shows that SkinCeuticals antioxidants neutralize free radicals on the upper layer of the skin to help prevent the impact of ozone damage to skin.2

**Protocol: 1-week clinical study on 12 subjects with 5 days of exposure to 0.8 ppm ozone for 3 hours per day. Subjects applied C E Ferulic and Phloretin CF to forearms for 3 days prior to ozone exposure. Product was left on skin for a minimum of 3 hours. Subjects continued with daily application of C E Ferulic and Phloretin CF for the entire duration of the study. Inclusion Criteria: Females and males ages 18-55 The Environmental Protection Agency (EPA) Air Quality Index categorizes ozone concentration at 0.404 ppm (parts per million) / 1 hr. and above as very unhealthy air. People who are sensitive to ozone experience severe respiratory symptoms (aggravated cough or pain) and impaired breathing.

A FIRST-EVER ANTI-AGING DISCOVERY

New ground-breaking SkinCeuticals science shows over-exposure to ozone pollution may cause visible skin aging, and topical antioxidant use can help prevent the impact of ozone damage to skin.

For the first time ever, SkinCeuticals C E FERULIC and PHLORETIN CF antioxidants were shown to help shield against signs of skin-aging induced by ozone (O3) pollution.1

*Protocol: 1-week clinical study on 12 subjects with 5 days of exposure to 0.8 ppm ozone for 3 hours per day. Subjects applied C E Ferulic and Phloretin CF to forearms for 3 days prior to ozone exposure. Product was left on skin for a minimum of 3 hours. Subjects continued with daily application of C E Ferulic and Phloretin CF for the entire duration of the study. Inclusion Criteria: Females and males ages 18-55 The Environmental Protection Agency (EPA) Air Quality Index categorizes ozone concentration at 0.404 ppm (parts per million) / 1 hr. and above as very unhealthy air. People who are sensitive to ozone experience severe respiratory symptoms (aggravated cough or pain) and impaired breathing.

SKINCEUTICALS ANTIOXIDANTS HELP SHIELD AGAINST OZONE-INDUCED ENVIRONMENTAL DAMAGE

#pollutionsolution

OZONE (O3) POLLUTION EXPLAINED

For years, scientific research on environmental causes of skin aging has focused solely on UV radiation. Today, ozone pollution is quickly becoming one of the most widespread threats to human respiratory health, with levels at the highest they’ve been in history.

What is ozone (O3) pollution?

What is ozone?

Ozone is a colorless gas that occurs both in the earth’s upper atmosphere and at ground level. Depending on its location in the atmosphere, ozone can be categorized as “good” or “bad”.

Stratospheric ozone, “good ozone,” creates a protective shield against damaging UV rays and is not a pollutant.

Tropospheric ozone, “bad ozone,” aggressively attacks respiratory tissue and is carcinogenic.

Source: Environmental Protection Agency
Source: World Health Organization

How is ground level ozone (O3) formed?

Tropospheric ozone is created by chemical reactions between oxides of nitrogen (NOx), volatile organic compounds (VOC), and sunlight.

Sources of NOx include automobile emissions and industrial sources such as power plants and industrial boilers. Man-made VOCs come from household and commercial products, as well as cigarette smoke, pesticides, and gasoline emissions.

Ground Level Ozone

Source: Environmental Protection Agency
Source: World Health Organization

What does this mean for skin?

What does this mean for skin?

Ground level ozone (O3) pollution is shown to cause signs of premature aging and can result in*:

  • • Increase in dehydration
  • • Increase in sebum production
  • • Increase in skin sensitivity
  • • Decrease in vitamin E

*Source: Evaluation of the impact of urban pollution on the quality of skin: a mulicentre study in Mexico

What is the comprehensive approach against ozone pollution and daily UV damage?

When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide a complimentary approach against visible aging caused by ozone pollution and UVA/UVB rays.