Dr. Sheldon R. Pinnell


Topical L-Ascorbic Acid Percutanous Absorption Studies Pinnell, S.R., et al.,Topical L-Ascorbic Acid: Percutaneous Absorption Studies.
Dermatol Surg 27:2, 137-142, 2001
SkinCeuticals was the first to discover the exact formulation specifications a topical antioxidant must meet in order to be effective on the skin. These parameters have become the gold standard for antioxidant formulation. UV Photoprotection by Combination Topical Antioxidants Vitamin C and E.
Lin, J.Y., Selim, M.A., Shea, C.R., Grichnik, J. M., Omar, M.M., Monterio-Riviere, N.A., and Pinnell, S.R. J Amer Acad Dermatol 48: 866-74, 2003.
SkinCeuticals second-generation product marks an important milestone in the development of antioxidant technology. For the first time, it was possible to mix successfully an aqueous antioxidant (Vitamin C) with an oily antioxidant (Vitamin E).
Photodamage and Oxidative Stress and Protection Provided by Topical Antioxidants
Pinnell, S.R, J Am Acad Dermatol. 48(1): 1-19, 2003.
In order to provide full-spectrum protection against environmentally caused skin damage, it is imperative to use a topical antioxidant daily. This added protection from free radicals has been proven to help prevent the appearance of premature skin aging.
Pinnell, S. et al. J Am Acad Dermatol. 59(3):418-25, 2008.
With SkinCeuticals third-generation topical antioxidant, C E Ferulic, it is possible to provide the skin with eight times its natural protection, as well as unprecedented anti-aging benefits. Additional peer-reviewed publications prove the ineffectiveness of other antioxidants – including alpha lipoic acid, ubiquinone, idebenone, and kinetin – in protecting skin from oxidative stress:
Alpha Lipoic Acid is Ineffective as a Topical Antioxidant for Photoprotection of Skin.
Lin, J.Y., Lin, F-H., Burch, J.A., Selim, M. Angelica, Monterio-Riviere, N.A., Grichnik, J. M. and Pinnell, S.R. J Invest Dermatol, 123:5, 996-998, 2004.
Ubiquinone, Idebenone, and Kinetin Provide Ineffective Photoprotection to Skin When Compared to a Topical Antioxidant Combination of Vitamins C And E with Ferulic Acid.
Tournas, J.A., Lin, F-H, Burch, J.A., Selim, M.A., Monteiro-Riviere, N.A., Zielinski, J.E., and Pinnell, S.R. J Invest Dermatol, 126, 1185-1187, 2006.

- J. Lamar Callaway Professor and Chief Emeritus of Dermatology at Duke University
- The Best Aesthetic Doctor in North America
- The Society for Investigative Dermatology, including honorary membership in 2012
- The Best Doctors in America
- The International Who’s Who in Medicine
- Who’s Who in Science and Engineering
- Who’s Who in America
- Diplomate of the American Board of Dermatology
- Member of the American Academy of Dermatology
- Member of the American Dermatological Association
- Member of the Society of Investigative Dermatology
- Member of the Association of American Physicians
The Pinnell Center serves as an enduring legacy of the faculty, staff and students’ appreciation and gratitude to Dr. Pinnell for his loyalty, mentoring, enthusiastic embrace of academic life, intellectual curiosity and outstanding leadership that has positioned Duke University’s Department of Dermatology as a national and world leader.