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Phloretin CF® with Ferulic Acid Vitamin C serum for face

Phloretin CF® with Ferulic Acid is rated 4.6 out of 5 by 99.
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A patented daytime vitamin c antioxidant face serum that delivers advanced environmental protection and diminishes the appearance of fine lines and discoloration. U.S. Patent No. 9,248,082.

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Product Details

Phloretin CF features a patented synergistic combination of 2% phloretin, 10% pure vitamin C (l-ascorbic acid), and 0.5% ferulic acid for enhanced protection against atmospheric skin aging – environmental damage and premature signs of aging caused by free radicals from UVA/UVB, infrared radiation (IRA), and ozone pollution (O3). In addition to antioxidant protective benefits, Phloretin CF improves the appearance of discoloration, fine lines, and uneven skin tone.

  • Provides advanced environmental protection by neutralizing damaging free radicals
  • Improves the appearance of discoloration and overall skin tone
  • Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours
  • Paraben-, fragrance-, and dye-free
  • Ideal for normal, oily, and combination skin types

How To Use

In the morning after cleansing and toning, apply 4-5 drops to a dry face, neck, and chest before other skincare products. May be used on the back of the hands. It is normal for vitamin C products to darken after opening due to air and light exposure. The formula will remain effective. Once opened, it is recommended to be used within 3 months of opening.

Complete your regimen with a SkinCeuticals sunscreen. When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide the most complete protection against visible aging caused by environmental aggressors.

  • Science & Proof

  • Science

    SkinCeuticals research shows that specific combinations of antioxidants, when effectively formulated, provide superior results to each single antioxidant formulation.

    Phloretin CF is a triple antioxidant cocktail formulation shown to provide broad-range environmental protection due to a synergistic combination of 2% phloretin, 10% pure vitamin C (L-ascorbic acid), and 0.5% ferulic acid. It is formulated under the Duke Antioxidant patent. Vitamin C is a highly-potent antioxidant that is, by its structure, difficult to effectively deliver on skin. The Duke Antioxidant patent describes the formulation parameters required for effective delivery of vitamin C to skin: 1) pure l-ascorbic acid (vitamin C); 2) an acidic pH within the 2.0-3.5 pH range and; 3) a concentration between 10%-20%. SkinCeuticals is the only brand to formulate antioxidants according to these parameters.


    SkinCeuticals defines atmospheric aging as the visible result of a range of environmental aggressors on skin, including UV, infrared radiation (IRA), and pollution. Ongoing SkinCeuticals research shows that over-exposure to these aggressors may cause visible skin aging, and topical antioxidants can help prevent the impact to skin.

    Learn more about atmospheric aging and ozone pollution

Key Ingredients

  • 2% phloretin
  • 10% L-ascorbic acid
  • 0.5% ferulic acid

Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, this antioxidant neutralizes damaging free radicals, helps improve cell turnover, and improves the appearance of discoloration

Learn more about phloretin

See all ingredients

aqua / water / eau, dipropylene glycol, alcohol denat., ascorbic acid, butylene glycol, triethyl citrate, phloretin, ferulic acid

Physician Insight

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I love patients to start the day with Phloretin CF to fight free radicals and smooth fine lines and wrinkles in the perfect concentration that our skin can use. We use an antioxidant for post-procedure homecare to complement results

Dr. Thomas Bender – Advanced Dermatology and SkinCare Centre

Learn about Dr. Thomas Bender

Complete Your Regimen


Rated 5 out of 5 by from Amazing results I have battled acne and it’s after effects for over 20 years. I have been on prescription medications including multiple rounds of accutane. This product is not a miracle, scarring and discoloration from sun damage and pregnancies were extensive. HOWEVER, my tone and texture have improved beyond my expectations and hopes. I can go out without makeup. I can stop hiding behind a cosmetic mask. I can let my husband touch my face without worrying it will smear. No product is magic, but this one has helped me regain my confidence that years of shame in my appearance have damaged. It feels good on, not greasy or thick, I wear every day under sunscreen. Highly recommend!
Date published: 2019-04-22
Rated 4 out of 5 by from Great product, but prefer C E ferulic This was the first antioxident by Skin Ceuticals that I tried. I'm now using the C E Ferulic and prefer it to this one. I didn't realize this one was for oily, problematic skin and ferulic for normal skin. Now I understand why this one dried and irritated my skin a little bit and ferulic doesn't. I don't think it would have been a problem if I wasn't a Retin-A user. Both are very good at reducing sun damage though! That's the main reason I use them because being a Retin-A user I can sunburn easily, but I don't have that problem anymore because of the anti-oxident before my sunblock. Highly recommend and totally worth the $$ if you ask me. I love SkinCeuticals products!
Date published: 2012-04-27
Rated 5 out of 5 by from Preventative yet produces immediate results! I have been using Phloretin CF since 2009 and have never gotten so many compliments on my skin before using this product. I am 31 years old and have spent a lot of time in the sun and have acne prone sensitive skin and people really think that I'm still in my early 20s or younger! I have even been accused of having botox since I started using this product! Also, the texture of my skin is so much softer and supple. I'm a grad student on a budget so all of my other skin care products are over the counter except for this amazing serum! It's so worth the money and it lasts for a long time! If you are looking for all skin care products in one bottle, this is the product for you!
Date published: 2011-08-08
Rated 5 out of 5 by from WORTH IT I was wary at the spa to purchase this product due to the price, so my aesthetician gave me a sample and said that I'd love it. I used it at first just once a week, then two or three times a week, and now I refuse to not include it in my daily skincare regimen. When I used the product sporadically, my employees and customers would comment on the glowing nature of my skin on the days that i used it. Interestingly, I always seemed to look tired or just different (I can't really articulate the difference, to be honest) when I didn't use the product in the morning. Now that I use it regularly, my skin is soft, smooth and beautiful. I feel more beautiful than I ever have.
Date published: 2011-07-30
Rated 5 out of 5 by from The Holy Grail I can honestly say that I have tried everything under the sun - every new product, every expensive product, everything the dermatologist or facialist recommends. My first foray into the Skinceuticals line was the CE Ferulic serum. I loved it, but someone mentioned trying Phloretin CF. I have combination skin, decent texture, but could use some improvement, and minor dark spots, but after using this product I look as if I got back from vacation and had a facial. It does wonders for my skin! Every time I take a break from it and try something else I remember why this is my go to product!
Date published: 2011-09-22
Rated 1 out of 5 by from No results I bought this product from a verified seller at the beginning of April and have used this every single day since then with no results. I make sure to not use any product that will cancel out the effects of this product, I pat it in, I make sure it is totally dry before applying anything else to my skin, and use an SPF yet I haven't noticed a single result so far. After two months I thought I'd notice at least a single dark spot fading but haven't even gotten that far yet. I'll continue to use this product until it is empty just for the pure fact it is so expensive but I don't see me buying this ever again in the future.
Date published: 2019-06-04
Rated 4 out of 5 by from Still Trying it Out I got a sample of the Phloretin CFwith a Skinceuticals purchase I made. I'm not sure which product, or if the combination of products, gave me results, but I have seen results in a short amount of time. Since this was such a small sample, I'm not sure of the results from it. My face was uncomfortably dry and tight. Since using Skinceuticals, my skin feels healthy and looks dewy. I also have extremely sensitive skin and will get rashes and hives to certain ingredients, but have had no reaction to Skinceuticals products! This serum has a watery consistensy and no smell, which is a plus!
Date published: 2019-04-22
Rated 2 out of 5 by from No difference I am in Canada so I have to get these products from a dermatologist as Skinceauticals does not ship to Canada. I have used a full bottle of Phloretin on the advice of my dermatologist. It lasted about a year. On my own I tried CE Ferulic. It has lasted about a year as well. I am 47 and have some discoloration due to sun damage and smile lines and crows feet. I have used these products for two years straight and still have the same skin. I use sunscreen as well and a serum from a different company. They have not made a difference honestly. Should I try an anti aging product from this line?
Date published: 2017-05-04
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