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Learn more.Product Details
Phloretin CF features a patented synergistic combination of 2% phloretin, 10% pure vitamin C (l-ascorbic acid), and 0.5% ferulic acid for enhanced protection against atmospheric skin aging – environmental damage and premature signs of aging caused by free radicals from UVA/UVB, infrared radiation (IRA), and ozone pollution (O3). In addition to antioxidant protective benefits, Phloretin CF improves the appearance of discoloration, fine lines, and uneven skin tone.
- Provides advanced environmental protection by neutralizing damaging free radicals
- Improves the appearance of discoloration and overall skin tone
- Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours
- Paraben-, fragrance-, and dye-free
- Ideal for normal, oily, and combination skin types
How To Use
In the morning after cleansing and toning, apply 4-5 drops to a dry face, neck, and chest before other skincare products. May be used on the back of the hands. It is normal for vitamin C products to darken after opening due to air and light exposure. The formula will remain effective. Once opened, it is recommended to be used within 3 months of opening.
Complete your regimen with a SkinCeuticals sunscreen. When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide the most complete protection against visible aging caused by environmental aggressors.
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Science & Proof

SkinCeuticals research shows that specific combinations of antioxidants, when effectively formulated, provide superior results to each single antioxidant formulation.
Phloretin CF is a triple antioxidant cocktail formulation shown to provide broad-range environmental protection due to a synergistic combination of 2% phloretin, 10% pure vitamin C (L-ascorbic acid), and 0.5% ferulic acid. It is formulated under the Duke Antioxidant patent. Vitamin C is a highly-potent antioxidant that is, by its structure, difficult to effectively deliver on skin. The Duke Antioxidant patent describes the formulation parameters required for effective delivery of vitamin C to skin: 1) pure l-ascorbic acid (vitamin C); 2) an acidic pH within the 2.0-3.5 pH range and; 3) a concentration between 10%-20%. SkinCeuticals is the only brand to formulate antioxidants according to these parameters.
SHIELD AGAINST ATMOSPHERIC AGING
SkinCeuticals defines atmospheric aging as the visible result of a range of environmental aggressors on skin, including UV, infrared radiation (IRA), and pollution. Ongoing SkinCeuticals research shows that over-exposure to these aggressors may cause visible skin aging, and topical antioxidants can help prevent the impact to skin.
Learn more about atmospheric aging and ozone pollution
Key Ingredients
- 2% phloretin
- 10% L-ascorbic acid
- 0.5% ferulic acid
Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, this antioxidant neutralizes damaging free radicals, helps improve cell turnover, and improves the appearance of discoloration
Learn more about phloretinSee all ingredients
aqua / water / eau, dipropylene glycol, alcohol denat., ascorbic acid, butylene glycol, triethyl citrate, phloretin, ferulic acid
Physician Insight

I love patients to start the day with Phloretin CF to fight free radicals and smooth fine lines and wrinkles in the perfect concentration that our skin can use. We use an antioxidant for post-procedure homecare to complement results
Dr. Thomas Bender – Advanced Dermatology and SkinCare Centre
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