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Phloretin CF® with Ferulic Acid Vitamin C serum for face

Phloretin CF® with Ferulic Acid is rated 4.6 out of 5 by 53.
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A patented daytime vitamin c antioxidant face serum that delivers advanced environmental protection and diminishes the appearance fine lines and discoloration. U.S. Patent No. 9,248,082.

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Product Details

Phloretin CF features a patented synergistic combination of 2% phloretin, 10% pure vitamin C (l-ascorbic acid), and 0.5% ferulic acid for enhanced protection against atmospheric skin aging – environmental damage and premature signs of aging caused by free radicals from UVA/UVB, infrared radiation (IRA), and ozone pollution (O3). In addition to antioxidant protective benefits, Phloretin CF improves the appearance of discoloration, fine lines, and uneven skin tone.

  • Provides advanced environmental protection by neutralizing damaging free radicals
  • Improves the appearance of discoloration and overall skin tone
  • Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours
  • Paraben-, fragrance-, and dye-free
  • Ideal for normal, oily, and combination skin types

How To Use

In the morning after cleansing and toning, apply 4-5 drops to a dry face, neck, and chest before other skincare products. May be used on the back of the hands. It is normal for vitamin C products to darken after opening due to air and light exposure. The formula will remain effective. Once opened, it is recommended to be used within 3 months of opening.

Complete your regimen with a SkinCeuticals sunscreen. When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide the most complete protection against visible aging caused by environmental aggressors.

  • Science & Proof

  • Science

    SkinCeuticals research shows that specific combinations of antioxidants, when effectively formulated, provide superior results to each single antioxidant formulation.

    Phloretin CF is a triple antioxidant cocktail formulation shown to provide broad-range environmental protection due to a synergistic combination of 2% phloretin, 10% pure vitamin C (L-ascorbic acid), and 0.5% ferulic acid. It is formulated under the Duke Antioxidant patent. Vitamin C is a highly-potent antioxidant that is, by its structure, difficult to effectively deliver on skin. The Duke Antioxidant patent describes the formulation parameters required for effective delivery of vitamin C to skin: 1) pure l-ascorbic acid (vitamin C); 2) an acidic pH within the 2.0-3.5 pH range and; 3) a concentration between 10%-20%. SkinCeuticals is the only brand to formulate antioxidants according to these parameters.


    SkinCeuticals defines atmospheric aging as the visible result of a range of environmental aggressors on skin, including UV, infrared radiation (IRA), and pollution. Ongoing SkinCeuticals research shows that over-exposure to these aggressors may cause visible skin aging, and topical antioxidants can help prevent the impact to skin.

    Learn more about atmospheric aging and ozone pollution

Key Ingredients

  • 2% phloretin
  • 10% L-ascorbic acid
  • 0.5% ferulic acid

Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, this antioxidant neutralizes damaging free radicals, helps improve cell turnover, and improves the appearance of discoloration

Learn more about phloretin

See all ingredients

aqua / water / eau, dipropylene glycol, alcohol denat., ascorbic acid, butylene glycol, triethyl citrate, phloretin, ferulic acid

Physician Insight

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I love patients to start the day with Phloretin CF to fight free radicals and smooth fine lines and wrinkles in the perfect concentration that our skin can use. We use an antioxidant for post-procedure homecare to complement results

Dr. Thomas Bender – Advanced Dermatology and SkinCare Centre

Learn about Dr. Thomas Bender

Complete Your Regimen


Rated 4 out of 5 by from Great product, but prefer C E ferulic This was the first antioxident by Skin Ceuticals that I tried. I'm now using the C E Ferulic and prefer it to this one. I didn't realize this one was for oily, problematic skin and ferulic for normal skin. Now I understand why this one dried and irritated my skin a little bit and ferulic doesn't. I don't think it would have been a problem if I wasn't a Retin-A user. Both are very good at reducing sun damage though! That's the main reason I use them because being a Retin-A user I can sunburn easily, but I don't have that problem anymore because of the anti-oxident before my sunblock. Highly recommend and totally worth the $$ if you ask me. I love SkinCeuticals products!
Date published: 2012-04-27
Rated 5 out of 5 by from Preventative yet produces immediate results! I have been using Phloretin CF since 2009 and have never gotten so many compliments on my skin before using this product. I am 31 years old and have spent a lot of time in the sun and have acne prone sensitive skin and people really think that I'm still in my early 20s or younger! I have even been accused of having botox since I started using this product! Also, the texture of my skin is so much softer and supple. I'm a grad student on a budget so all of my other skin care products are over the counter except for this amazing serum! It's so worth the money and it lasts for a long time! If you are looking for all skin care products in one bottle, this is the product for you!
Date published: 2011-08-08
Rated 5 out of 5 by from WORTH IT I was wary at the spa to purchase this product due to the price, so my aesthetician gave me a sample and said that I'd love it. I used it at first just once a week, then two or three times a week, and now I refuse to not include it in my daily skincare regimen. When I used the product sporadically, my employees and customers would comment on the glowing nature of my skin on the days that i used it. Interestingly, I always seemed to look tired or just different (I can't really articulate the difference, to be honest) when I didn't use the product in the morning. Now that I use it regularly, my skin is soft, smooth and beautiful. I feel more beautiful than I ever have.
Date published: 2011-07-30
Rated 5 out of 5 by from The Holy Grail I can honestly say that I have tried everything under the sun - every new product, every expensive product, everything the dermatologist or facialist recommends. My first foray into the Skinceuticals line was the CE Ferulic serum. I loved it, but someone mentioned trying Phloretin CF. I have combination skin, decent texture, but could use some improvement, and minor dark spots, but after using this product I look as if I got back from vacation and had a facial. It does wonders for my skin! Every time I take a break from it and try something else I remember why this is my go to product!
Date published: 2011-09-22
Rated 2 out of 5 by from No difference I am in Canada so I have to get these products from a dermatologist as Skinceauticals does not ship to Canada. I have used a full bottle of Phloretin on the advice of my dermatologist. It lasted about a year. On my own I tried CE Ferulic. It has lasted about a year as well. I am 47 and have some discoloration due to sun damage and smile lines and crows feet. I have used these products for two years straight and still have the same skin. I use sunscreen as well and a serum from a different company. They have not made a difference honestly. Should I try an anti aging product from this line?
Date published: 2017-05-04
Rated 1 out of 5 by from phloretin cf i have been using ce ferulic for a long time, when i heard abt phloretin cf i wanted to try this out as i was told this is better for combination n oily skin...i tried it n after only 4 days of use got big bumps in the skin as if there was a huge pimple under the skin--got quite a few of these. my skin looked baaaad,,,was so disappointed by this product as i love skinceuticals ce ferulic n retexturising activator. plz dont use if u have sensitive skin or are allergic to alcohol--when i called the skinceuticals rep she told me that this product has alcohol too...hated this product.will return to my ce ferulic, love that product.. buy this only from, not from doctors offices...had a bad experience twice ,theysold me expired bottles,found this out when i called skinceuticals with the batch number on the bottle to enquire if it was fresh or not,both times i was told it had expired. so if u buy from an office/spa, call skinceuticals with the batch number on the box to enquire its effectiveness.
Date published: 2010-10-11
Rated 4 out of 5 by from Already seeing results As a fair skinned, red head who has extremely sensitive skin, I am reluctant to try any new skin product, let alone something so expensive. After this product was used at a facial and I didn't have an allergic reaction, I decided to give this a try. I have been using it for almost 2 weeks and my problem areas are almost gone. I bought the CE one too since this one is pretty drying. I have not had any reactions to either product which says a lot. I will be continuing to use!
Date published: 2013-03-10
Rated 5 out of 5 by from Essential. Don't leave home without applying it. My review: I discovered Skinceuticals in 2008, thanks to my dermatologist. Registered on your Website soon after. I swear by Phloretin CF, that stuff is magic, in the sense that you feel it working as soon as you apply it. The eye dropper ...bottle technique is ideal, as you only use as much as you need. I find 'just a ginger' amount does the trick. After putting CF on, then applying my helioplex sunscreen, I know I'm protected by the nasty UVA and UVB rays. (With just suncreen, my skin feels naked by comparison.)
Date published: 2010-11-12
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