Azelaic Acid

Azelaic acid is a natural dicarboxylic acid derived from grains such as wheat, barley, and rye¹, although the azelaic acid found in skincare products is generally synthesized in a lab. Though not an alpha- or beta-hydroxy acid, azelaic acid can provide gentle exfoliation to stimulate cell turnover,² and this ingredient offers additional skin benefits that AHAs and BHAs do not.

¹ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843359/
² https://www.healthline.com/health/azelaic-acid-acne

Azelaic acid offers a wide variety of benefits for the skin. Research has found that this ingredient has been found to provide improvement in the appearance of skin discoloration and skin clarity¹. Azelaic acid also has antioxidant properties and is recognized as an anti-comedogenic, which means it will not contribute to acne breakouts.²

Azelaic acid can be beneficial for a broad range of skin types and tones.¹ As an antioxidant, it helps neutralize the free radicals that lead to environmental damage in all skin types . Research has shown that free radical oxidation may play a role in acne formation as well, making azelaic acid’s antioxidant properties beneficial for blemish-prone skin.²

Azelaic acid has been proven to be an effective ingredient for improving the appearance of skin discoloration, including dark spots caused by acne scars. In fact, twice-daily use of prescription-grade 20% azelaic acid has been found to be more effective than 4% hydroquinone for discoloration caused by melasma.¹

Azelaic acid can be found in over-the-counter as well as prescription-based skincare products, including serums, creams, gels, and foams. Yet one of the most innovative ways to incorporate azelaic acid into your skincare routine is with SkinCeuticals’ Custom D.O.S.E. This cutting-edge, office-based service uses a patented skin-diagnostic tool that allows skincare professionals to create a customized corrective serum that addresses each patient’s unique skin type and concerns. Azelaic acid is often included in formulas for those concerned about skin discoloration, and this ingredient may also be recommended for improving skin clarity as well as the appearance of other types of imperfections.

Yes, you can use formulas containing azelaic acid as often as twice every day. If you worry about possible skin irritation when starting the use of formulas containing azelaic acid, start by using it two or three times a week, then work up to daily use.

Yes, you can use formulas containing azelaic acid for the skin with retinol. These two ingredients work synergistically to improve the appearance of skin by reducing discoloration and other imperfections by stimulating cellular turnover.

Yes, vitamin C can be used with azelaic acid in skincare. Vitamin C and azelaic acid are effective at reducing hyperpigmentation. These ingredients work synergistically as vitamin C helps to heal the skin while azelaic acid improves the skin’s cellular turnover rate.