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Discoloration Defense Skin discoloration serum

Discoloration Defense is rated 3.7 out of 5 by 108.
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Daily dark spot corrector targets visible skin discoloration for brighter, more even-looking skin

skin types

Dry
Normal
Oily
Combination

skin condition

Discoloration

$98.00

Availability:

In Stock

Product Details

Discoloration Defense is a layerable, daily-use dark spot corrector clinically proven to reduce the appearance of key types of skin discoloration, including hard-to-treat forms such as stubborn brown patches and post-acne marks. Formulated with 3% tranexamic acid, 1% kojic acid, 5% niacinamide, and 5% HEPES, this latest-generation formula improves the appearance of skin discoloration, brightens skin, and evens skin tone in as early as 2 weeks.

  • Features a synergistic blend of anti-discoloration ingredients to reduce the appearance of skin discoloration, improve brightness, and minimize the reoccurrence of discoloration (with continued use)
  • 60% average improvement in the appearance of stubborn brown patches
  • Paraben-, fragrance-, silicone-, gluten-, and hydroquinone-free
  • Ideal at-home complement to professional skin discoloration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations

How To Use

  • Twice daily, apply 3-5 drops of this skin discoloration serum to the face.
  • If using in the morning, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad spectrum SPF 50+ sunscreen.
  • Limit sun exposure while using this product.
  • Do not use on irritated or broken skin. If irritation occurs, discontinue use.
  • Visible Results

  • before
    after

    In a 12-week clinical study, Discoloration Defense significantly improved the appearance of key skin discoloration markers:

    • 60% average improvement in the appearance of stubborn brown patches
    • 59% average improvement in the appearance of skin discoloration
    • 81% average improvement in the appearance of post-acne marks
    • 59% average improvement in the appearance of even skin tone

    See Protocol

    Protocol: Average results shown. A 12-week, single-center, clinical study was conducted on 50 females, ages 25 to 60, Fitzpatrick I-IV, with mild to moderate facial skin discoloration, including stubborn dark spots, post-acne marks, and uneven skin tone. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.

  • Science & Proof


  • Science

    Everyday elements—including UV exposure, prescription drugs, and some professional treatments—can trigger production of melanin in the skin’s lowest epidermal layers. This excess melanin rises to the surface of the skin, causing visible skin discoloration. Discoloration can manifest in a range of ways, including post-acne marks and stubborn brown patches on the cheekbones, forehead, and upper lip.

    Discoloration Defense is the latest-generation dark spot corrector, using a combination of potent and proven anti-discoloration ingredients—including new tranexamic acid—to address key types of skin discoloration.

Key Ingredients

  • 3% Tranexamic Acid
  • 1% Kojic Acid
  • 5% Niacinamide
  • 5% HEPES

This synthetically-derived ingredient minimizes the reoccurrence of skin discoloration and stubborn brown patches with continued use.

Learn more about Tranexamic Acid

See all ingredients

Aqua / Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Tranexamic Acid, Propylene Glycol, Hydroxyethyl Urea, Kojic Acid, Caprylyl Glycol, Allantoin, Chlorphenesin, Xanthan Gum, Disodium Edta

Physician Insight

Physician image

I recommend Discoloration Defense between chemical peels- this formula targets stubborn types of discoloration but is gentle on my patients’ skin, making it ideal for an at-home regimen between treatments.

Dr. Sarah Sawyer

Learn about Dr. Sarah Sawyer

Complete Your Regimen

Reviews

Rated 5 out of 5 by from Great product, but I think it oxidized? I absolutely love this product. It has been such a game changer for my hyper-pigmentation. However, the serum has turned to a dark orange/brown. Can I still use it?
Date published: 2020-09-15
Rated 1 out of 5 by from Don’t waste your money I bought this to lighten my ugly moles and I’ve been using for a week and there is no change at all. I’ve been trying to get rid of my moles from the sun forever. I’m hopeless now.
Date published: 2020-09-08
Rated 2 out of 5 by from No improvement I've tried many skinceuticals products and some work for my skin and others don't. This on. unfortunately has not at all after using the full bottle. I will go back to Phyto for discoloration which has worked better for me.
Date published: 2020-09-05
Rated 5 out of 5 by from Effective. Received a sample with a order and found it very effective. Absorbs quickly, has no smell (yay!), and I saw results faster than expected. Ordered more before sample was gone. Now a staple in my skin care. Impressed.
Date published: 2020-08-28
Rated 3 out of 5 by from Sample I wish I could give review on the sample product I received. But when I opened the sample packet. It spilled out all over my hand. I can not give you an honest opinion on the product I received except the packaging needs to be improved. But in the past I have used several of Skinceuticals products. I have always been pleased with the results of other products.
Date published: 2020-08-21
Rated 1 out of 5 by from Discoloration Defense I received a sample packet of this when I cut and tried to squeeze out a small amount all of the serum squirted out. Company has to figure out how to better package a sample. I have been using the A.G.E Interrupter for the face for six weeks with no results so I am not purchasing this. These products are not cheap I expect a usable sample and results will not purchase any products in the future.
Date published: 2020-08-17
Rated 5 out of 5 by from Amazing product This was recommended by our dermatologist for treating pigmentation and after 1 month, we can see the pigmentation has faded quite a bit already.
Date published: 2020-08-16
Rated 1 out of 5 by from Review There wasn't enough on that sample sheet to be able to tell a difference.
Date published: 2020-08-09
  • y_2020, m_9, d_21, h_15
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.12
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_108
  • loc_en_US, sid_3606000481244, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_skinceuticals-us
  • bvseo_sdk, dw_cartridge, 17.1.0, p_sdk_3.2.0
  • CLOUD, getReviews, 8ms
  • reviews, product