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Glycolic 10 Renew Overnight Glycolic Acid Cream

Glycolic 10 Renew Overnight is rated 4.4 out of 5 by 65.
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Nighttime glycolic acid cream delivers a true 10% glycolic acid value to promote cellular turnover for healthy, glowing skin

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Product Details

Glycolic 10 Renew Overnight is formulated with a free acid value of 10% glycolic acid, allowing it to work at a true 10% concentration proven optimal in promoting effective exfoliation and natural cell turnover. Free acid value refers to the true strength of a glycolic acid product, and is affected by both the concentration of acid and the pH of the formula. This potent night cream is synergistically blended with 2% phytic acid to promote skin clarity and brightness, and a triple action-soothing complex to help support the skin barrier. Proven tolerable for nightly use, Glycolic 10 Renew Overnight improves the appearance of skin texture and tone to promote a bright complexion and glowing skin.

  • Features a free acid value of 10% glycolic acid to promote cellular turnover
  • 36% average improvement in glowing skin
  • Dye-, and fragrance-free
  • Tested tolerable for nightly use
  • Ideal complement to chemical peels to pre-condition skin and extend results; always consult with a physician for individual regimen recommendations

How To Use

• Shake before use.

• Some skin types may require time to acclimate to glycolic acid. In these cases, precondition skin for this night cream by limiting initial use to once every other evening.

• Apply an even, pea-sized layer over entire face and neck. After one week, increase to every evening or as advised by a skincare professional.

• Avoid eye area.

• Always use with a daytime antioxidant + sunscreen.

• With use of a high-concentration glycolic acid, it is common to experience mild symptoms of skin detoxification such as redness and temporary skin purging. Generally, these side effects resolve with continual use.

  • Visible Results

  • visible results

    In an 8-week clinical study, Glycolic 10 Renew Overnight significantly improved the appearance of key markers of glowing skin:

    • 36% average improvement in radiance
    • 37% average improvement in skin texture
    • 19% average improvement in skin tone

    See Protocol

    Protocol: An 8-week, single-center, clinical study was conducted on 50 females, ages 35-64, with global fine lines, uneven skin tone, rough skin texture, and a dull complexion. Glycolic 10 Renew Overnight was used once nightly in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, and 8. Images represent the composite mapping of surface light scattering and volume light scattering of photographs collected under diffused light. Photos representative of average results. Your results may be greater or less than the average.

  • Science & Proof

  • Science

    Not every glycolic acid cream is created equal. The effectiveness of glycolic acid is determined by its free acid value, which depends on 2 factors:

    1.Concentration: a 4-10% glycolic acid is the ideal concentration for nightly use
    2. pH: low pH formulas preserve the strength of the glycolic acid for optimal efficacy on skin

    Glycolic 10 Renew Overnight is formulated with a concentration of glycolic acid that delivers a true 10% glycolic free acid value in a 3.5 pH formula tolerable for nightly use. This potent glycolic acid cream is complemented by a soothing complex of botanicals and oils, along with a 2% phytic acid to improve texture, radiance, and overall glow.

Key Ingredients

  • 10% Glycolic Free Acid Value
  • 2% Phytic acid
  • 1% Soothing complex

Derived from sugar cane, this powerful fruit acid helps stimulate skin’s natural exfoliation process and minimizes the buildup of dead skin cells, resulting improvement in the appearance of skin texture, tone, and a brighter complexion.

Learn more about Glycolic acid

See all ingredients

Aqua/Water, Glycolic Acid, Dicaprylyl Carbonate, Dimethicone, Sodium Hydroxide, Butylene Glycol, Propanediol, Glycerin, Phytic Acid, Cetyl PEG/PPG-10/1 Dimethicone, Aluminum Starch Octenylsuccinate, Nylon-12, Poly-glyceryl-4 Isostearate, Magnesium Sulfate, Jojoba Esters, Phenoxyethanol, Helianthus Annuus Seed Cera/Sunflower Seed Wax, Caprylyl Glycol, Disodium EDTA, Salicylic Acid, Acacia Decurrens Flower Cera/Accia Decurrens Flower Wax, Polyglycerin-3, Tocopherol, Pentaerythrityl tetra-di-t-butyl Hydroxyhydrocinnamate

Physician Insight

Physician image

This glycolic product promotes exfoliation and glowing skin like no other. And, without causing dryness that is so prevalent with other products. A real “go to” to shed the dull and unveil your luster.

Dr. Patti Flint – Patti Flint, MD

Learn about Dr. Patti Flint

Complete Your Regimen


Rated 5 out of 5 by from What a difference! I recently purchased this glycolic 10 serum, as I am 46 years old, and would like to retain my youthful complexion. I suffer from dry spots and I'm starting to lose firmness, but this has dramatically changed that. I am so excited to have found SkinCeuticals. This product has made a huge difference in every other night use!! My complexion is smoother, fresh, and bright in appearance and I'm beginning to feel more suppleness. I've been using drugstore brand skincare but in just over one month of using this every other night (due to having hypoallergenic, sensitive skin) I feel great! My new skin care regimen consists of a good cleanser, toner, C E Furelic serum, triple lipid 242 moisturizer, and the glycol 10 and my skin has done a complete 180! I thought I had pretty good skin before.. The dramatic difference I saw in just a few days was well worth the price tag of this skin care line, but after 1 month I pay double LOL! Just kidding please don't raise the prices. I am now on my third order in just over one month.
Date published: 2021-02-10
Rated 3 out of 5 by from Needs improvement Poor delivery I am currently in the skin purge cycle. It is nice to get rid of the gunk but make sure you plan on pimples popping up. I'm really disappointed in the thickness of this. It is different than the sample and about the consistency of milk. The tube they place the product in is inferior and wastes large amounts of product. You're supposed to use a pea size amount but the tube squeezes the amount of two quarters out. You can't put it back in. What a waste! I shake it well as instructed. No matter how much you shake, it still runs everywhere. Very inefficient for such an expensive product.
Date published: 2021-01-25
Rated 3 out of 5 by from Tube broke I like the product. It keeps my skin feel clean but not drying out. However less than half way, the end of the tube broke.... when I squeeze it, the cleanser come out from both ends ....
Date published: 2021-01-22
Rated 4 out of 5 by from Incredible Product but horrible packaging I started using this after a medical facial, the aesthetician recommended it amongst other skinceuticals products and immediately became holy grail, but the packaging really needs work! Please please fix this as it’s such an expensive product so it’s really sad when so much of it squirts out at one time and gets wasted!
Date published: 2021-01-12
Rated 5 out of 5 by from Used with CE FURLIC and Overnight Retinol & WOW My daughter is an esthetician and she has me on the following SkinCeutical products: CE Ferulic and .5 Retinol Night cream and this Glycolic 10 Renew Overnight. I use the Glycolic Renew every couple days and the Retinol on the others. CE Ferulic is used twice daily. My skin peeled somewhat in the beginning but now my skin is brighter and plumper. Definitely sticking with it.
Date published: 2020-11-13
Rated 3 out of 5 by from Terrible packaging I’m still undecided on the product itself but the packaging is horrid! No matter how lightly I twist on the lid, the next time I use it tons has gushed out. I’m sad at how much product was wasted each time. Now I am storing it upside down in a mason jar with the lid on as tight as possible but there is still some spillage. It came highly recommended by my aesthetician so I will at least use up this bottle but I definitely think the packaging needs an upgrade. Maybe a pump similar to the Redness Neutralizer would be nice.
Date published: 2020-11-13
Rated 5 out of 5 by from Amazing! I've been using this product for about 6 months. I'm obsessed. This in combination with Triple Lipid Restore has made me look 10 years younger. I am about to turn 50.
Date published: 2020-11-09
Rated 5 out of 5 by from Incredible Results!! I waited a good 4 weeks before writing this review so I could write a more accurate description of my results. This renewal cream only needs to be used sparingly, esp. over the areas of breakouts. I had amazing results, and all of my blemishes disappeared at the end of week 2. You have to not use too much of it to where your face is left feeling greasy. If you don’t do this, then you’ll have more breakouts. I used very little, less than a dime, and it made my face feel so good! Another hint - put this on before your nightly moisturizers, and let it completely absorb into your skin before applying the others. I waited at least 10 min. before applying my nightly regimen. Try this and give it 2-4 weeks before giving up. As with any other skincare products, you will break out at first until your skin has time to adjust to the new ingredients. That’s why I waited to give a review!
Date published: 2020-11-08
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